Please use this identifier to cite or link to this item: https://idr.nitk.ac.in/jspui/handle/123456789/13463
Title: Solvent-free synthesis of bis-hydrazones through 1,3-dipolar cycloaddition of sydnone and study of their optical, molecular docking, and antioxidant properties
Authors: Asma
Kalluraya, B.
Manju, N.
Adhikari, A.V.
Chandra
Mahendra, M.
Issue Date: 2018
Citation: Indian Journal of Heterocyclic Chemistry, 2018, Vol.28, 3, pp.335-344
Abstract: A series of new 1-(aryl)-1H-pyrazol-3,4-bis (aryl)-3,4-dicarbohydrazones (4) was obtained by the condensation of 1-arylpyrazole-3,4-dicarbohydrazides (3) with various aryl aldehydes under solvent-free conditions. The structures of the newly synthesized hydrazones were confirmed by proton-nuclear magnetic resonance spectroscopy, infrared spectroscopy, liquid chromatography mass spectrometry, elemental analysis, and by single crystal X-ray diffraction. All the synthesized compounds were screened for their antioxidant activity, where compound 4a has shown percentage inhibition higher than the standard butylated hydroxyanisole. The molecular docking and photophysical property were also investigated. 2018 Connect Journals.
URI: http://idr.nitk.ac.in/jspui/handle/123456789/13463
Appears in Collections:1. Journal Articles

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