A catalyst- and solvent-free three-component reaction for the regioselective one-pot access to polyfunctionalized pyrroles
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Date
2013
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Abstract
A facile method for the regioselective synthesis of tetrasubstituted pyrroles, from readily accessible 1,3-dicarbonyls, benzoin derivatives and ammonium acetate, has been developed. The one-pot three-component reactions were performed to afford tetrasubstituted pyrroles under solvent- and catalyst-free conditions. © 2013 Elsevier Ltd. All rights reserved.
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Keywords
ammonium acetate, benzoin, carbonyl derivative, pyrrole derivative, article, catalyst, chemical reaction, stereochemistry, synthesis
Citation
Tetrahedron Letters, 2013, 54, 41, pp. 5577-5582