Processing and characterization of egg shell derived nano-hydroxyapatite synthetic bone for Orthopaedic and Arthroscopy implants and substitutes in dentistry
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Date
2023
Journal Title
Journal ISSN
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Publisher
Elsevier Ltd
Abstract
The present work is focused on the nano-Hydroxyapatite (nHAp) synthesis with two different Indian breed Aseel and Kadaknath eggshells. The alloplast implants were developed through the foam replica method with polyurethane 45-PPI as a porous template. The synthesized nHAp was characterized by Field Emission Scanning Electron Microscopy (FE-SEM), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR). The FE-SEM images of the nHAp showed the one dimensional clustered nanoparticles and the X-ray diffraction spectrum confirms that the major phase was hydroxyapatite with a small trace of β-tricalcium phosphate. The maximum compression strength of the sample was 5.49 ± 0.12 MPa which is in the range of the compression strength of human trabecular bone. The thermal and degradability studies results confirmed that these are highly stable and provides necessary a resorption needed for new bone tissue formation. Besides, the antimicrobial activity against tested human microbiome are satisfactory and the cell viability towards MG 63 human osteoblast-like cells provides a potential pathway for developing the nHAp implants for bone tissue engineering. © 2023 Elsevier Ltd
Description
Keywords
Bone, Cell engineering, Enamels, Field emission microscopes, Fourier transform infrared spectroscopy, Nanocomposites, Scanning electron microscopy, Tissue engineering, X ray diffraction, Alloplast, Compression strength, Egg shells, Field emission scanning electron microscopy, Hydroxyapatite synthesis, Nano-hydroxyapatite, Porous templates, Replica method, Synthetic bone, Trabecular bone tissue, Hydroxyapatite, calcium phosphate, hydroxyapatite, nanohydroxyapatite, polyurethan, N-hydroxy-2-aminopyrene, antimicrobial activity, arthroscopy, Article, biodegradability, bone tissue, Candida albicans, cell viability, compression, controlled study, egg shell, Escherichia coli, field emission scanning electron microscopy, foam, human, human cell, MG-63 cell line, microbiome, nonhuman, ossification, osteoblast, porosity, Staphylococcus aureus, strength, synthesis, trabecular bone, animal, bone, chemistry, dentistry, orthopedics, procedures, tissue engineering, Animals, Arthroscopy, Bone and Bones, Dentistry, Durapatite, Egg Shell, Humans, Orthopedics, Spectroscopy, Fourier Transform Infrared, Tissue Engineering, Tissue Scaffolds, X-Ray Diffraction
Citation
Journal of the Mechanical Behavior of Biomedical Materials, 2023, 144, , pp. -