Sikdar, A.Roy, S.Haldar, K.Sarkar, S.Panja, S.S.2026-02-052013Journal of Fluorescence, 2013, 23, 3, pp. 495-50110530509https://doi.org/10.1007/s10895-013-1169-yhttps://idr.nitk.ac.in/handle/123456789/26792A rhodamine B-based fluorescence probe (1) for the sensitive and selective detection of Cu2+ ion has been designed and synthesized using pyridine moiety. The optical properties of this compound have been investigated in acetonitrile-water binary solution (7:3 v/v). Compound 1 is found to be an excellent sensor for a biologically/physiologically very important transition metal ion (Cu2+) using only the two very different modes of measurements (absorption and emission); one case displayed intensity enhancement whereas in other case showed intensity depletion (quenching). A mechanistic investigation has been performed to explore the static nature of quenching process. The sensor has been found to be very effective in sensing Cu 2+ ion inside living cells also. © 2013 Springer Science+Business Media New York.Absorption and emissionsChemo-sensorsFluorescence probesIntensity enhancementLiving cellRhodamine BSelective detectionStatic quenchingMetal ionsOptical propertiesPositive ionsSensorsSynthesis (chemical)copperfluorescent dyerhodaminerhodamine BSchiff basecell survivalchemical analysischemistrycytologydevicesEscherichia colispectrofluorometrysynthesisCell SurvivalChemistry Techniques, AnalyticalChemistry Techniques, SyntheticCopperFluorescent DyesRhodaminesSchiff BasesSpectrometry, Fluorescence