Kolay, S.Kancharlapalli, S.Samanta, S.Muhiuddin, M.Jha, P.Pagare, A.Mishra, R.2026-02-032025Industrial and Engineering Chemistry Research, 2025, 64, 18, pp. 9140-91528885885https://doi.org/10.1021/acs.iecr.4c04840https://idr.nitk.ac.in/handle/123456789/20271Owing to the rapid growth of nuclear energy as a sustainable, affordable, and clean energy source, the entrapment of radioactive iodine released from the nuclear off-gas stream is considered a vital concern. We view MOFs as potential futuristic adsorbents for this remedy. Herein, we examined the gravimetric iodine adsorption characteristics of radiation and chemically stable MIL-101(Cr) and its polymeric composites with variation of temperatures. The saturation adsorption capacity shown by pristine MIL-101(Cr) is 4.1 g I<inf>2</inf> g-1, and the saturation capacity of composites varies based on MIL-101(Cr)’s concentrations. MIL-101(Cr)@PES 2:1 shows an uptake capacity of 2.1 g I<inf>2</inf> /g<inf>bead</inf>, which is ? 350% superior to the reported HKUST-1@PES and ?150% higher compared to MOF-808@PVDF<inf>0.7</inf>. Based on various spectroscopic studies and DFT calculations, probable host-guest interactions leading to enhanced I<inf>2</inf> adsorption have been elucidated. The open Cr metal site acts as the initial adsorption site for I<inf>2</inf> that gets converted into iodide and afterward to higher polyiodide through the transfer of charge from the host matrix. These findings suggest that MIL-101(Cr) can be considered one of the potential alternate adsorbents for radioactive iodine. © 2025 American Chemical Society.Gas adsorptionIodine compoundsMendeleviumNuclear energyRadioactivityClean energy sourcesComputational studiesEnergyGas streamsOff-gasesPolymeric compositesPotential adsorbentsRadioactive iodineRapid growthSustainable energy sourcesSpectroscopic analysis