Vrushabendra Swamy, S.B.M.Nataraj, K.S.Jayaveera, K.N.Gopkumar, P.Nayak, S.Kumar, G.S.Umachigi, S.P.2026-02-052007Pharmacologyonline, 2007, 3, , pp. 1-1418278620https://idr.nitk.ac.in/handle/123456789/27785A study was undertaken to evaluate the effect of methanolic extract of the rootbark of Aegle marmelos Corr. (MAMC) against several experimental models of diarrhoea in rats. MAMC treated animal's showed significant inhibitory effect against castor-oil induced diarrhea and PGE<inf>2</inf> induced enteropooling in rats. The extract also showed a significant reduction in gastrointestinal motility in the charcoal meal test in rats. The results obtained to establish the efficacy and substantiate the folkare claim as an anti-diarrhoeal agent.Aegle marmelos extractatropinecastor oildiphenoxylatemethanolprostaglandin E2animal experimentanimal modelanimal tissuearticlebarkcontrolled studydiarrheadrug dose comparisondrug efficacydrug mechanismdrug screeningfemalegastrointestinal motilityLD 50malenonhumanplant rootrattoxicity testingWistar rat