Holla, M.R.Pais, A.R.2026-02-042022Applied Intelligence, 2022, 52, 14, pp. 16852-168680924669Xhttps://doi.org/10.1007/s10489-021-03095-7https://idr.nitk.ac.in/handle/123456789/22353Visual Secret Sharing (VSS) is a field of Visual Cryptography (VC) in which the secret image (SI) is distributed to a certain number of participants in the form of different encrypted shares. The decryption then uses authorized shares in a pre-defined manner to obtain that secret information. Medical image secret sharing (MISS) is an emerging VSS field to address the performance challenges in sharing medical images, such as efficiency and effectiveness. Here, we propose a novel MISS for the histopathological medical images to achieve high performance in these two parameters. The novelty here is the Graphics Processing Unit (GPU) to exploit the data-parallelism in MISS during encryption and super-resolution (SR), supplementing effectiveness with efficiency. A Convolution Neural Network (CNN) for SR produces a high-contrast reconstructed image. We evaluate the presented model using standard objective assessment parameters and the Computer-Aided Diagnosis (CAD) systems. The result analysis confirmed the high-performance of the proposed MISS with a 98% SSIM of the deciphered image. Compared with the state-of-art deep learning models designed for the histopathological medical images, MISS outperformed with 99.71% accuracy. Also, we achieved a categorization precision that fits the CAD systems. We attained an overall speedup of 800 × over the sequential model. This speedup is significant compared to the speedups of the benchmark GPGPU-based medical image reconstruction models. © 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.Computer aided designComputer aided diagnosisComputer graphicsConvolutionCryptographyDeep learningEfficiencyImage reconstructionMedical imagingOptical resolving powerProgram processorsComputer aided diagnosis systemsConvolution neural networkHalftoningImage secret sharingPerformanceReconstructionShadowSuperresolutionVisual cryptographyVisual secret sharingGraphics processing unit