Prasad, R.Gorjizadeh, N.Rajarao, R.Sahajwalla, V.Badekai Ramachandra, B.R.2026-02-052015RSC Advances, 2015, 5, 56, pp. 44792-44799https://doi.org/10.1039/c5ra03720dhttps://idr.nitk.ac.in/handle/123456789/26398Herein, in this work we synthesized plant root nodule like NiO-MWCNT nanocomposites by a simple, rapid and solvent-free method using nickel formate as a precursor. Using a first-principle simulation study the interactions and charge transfer behaviour of the NiO and MWCNT composite is investigated. The as-prepared NiO-MWCNT composite is employed to fabricate a modified non-enzymatic carbon paste electrode (CPE) for glucose sensing. From the electrochemical investigation, the fabricated sensor shows an excellent sensitivity of 6527 ?A mM-1 cm-2 with a detection limit of 19 ?M and a linear response over a range from 0.001 mM to 14 mM of glucose concentrations, at an applied potential of 0.5 V. Importantly the sensor also exhibits greater stability, selectivity and reproducibility. A first principle simulation study shows the differences in charge density and charge transfer behaviour from nanotubes to NiO nanoparticles, which in turn enhances the electro catalytic property of the NiO-MWCNT composite. Hence, these results indicate that the NiO-MWCNT composite is a potential material for non-enzymatic electrochemical glucose sensors. This journal is © The Royal Society of Chemistry.CarbonCharge transferGlucoseGlucose sensorsNickelNickel oxideYarnCarbon paste electrodeCatalytic propertiesElectrochemical glucose sensorsElectrochemical investigationsFirst principle simulationGlucose concentrationNon-enzymatic glucose sensorsPotential materialsMultiwalled carbon nanotubes (MWCN)