Sekar, P.Nyahale, M.B.Naik, G.M.Narendranath, N.Prabhu, A.Rekha, P.D.2026-02-052021Journal of Materials Science: Materials in Medicine, 2021, 32, 6, pp. -9574530https://doi.org/10.1007/s10856-021-06535-5https://idr.nitk.ac.in/handle/123456789/23201The mechanical integrity of rolled ZM21 Mg was improved by equal channel angular pressing (ECAP) to function as a potential biodegradable bone screw implant. Electron backscattered diffraction (EBSD) revealed deformed grains of 45 µm observed in rolled ZM21 Mg. They were transformed to equiaxed fine grains of 5.4 µm after 4th pass ECAP. The yield strength of rolled and ECAPed ZM21 Mg alloys were comparable. In contrast, 4th pass ZM21 Mg exhibited relatively higher elongation when compared to rolled sample. The mechanical properties of rolled and ECAPed ZM21 Mg were dependant on both grain refinement and crystallographic texture. The rolled and 4th pass ECAPed tensile samples exhibited nonlinear deterioration of mechanical properties when tested after 7, 14, 21 and 28 days immersion in Hank’s solution. The evaluation signifies that regardless their processing condition, ZM21 Mg alloys are suitable for surgical areas that requires high mechanical strength. In addition, the 4th pass ECAP samples were viable to MG-63 cells proving themselves to be promising candidates for future in vivo studies. [Figure not available: see fulltext.] © 2021, The Author(s).DeteriorationGrain refinementGrain size and shapeMagnesium alloysMechanical propertiesMicrobial corrosionPressing (forming)TexturesCrystallographic texturesDeformed grainsElectron back-scattered diffractionFine grainsHigh mechanical strengthMechanical integrityOrthopaedic implantsProcessing conditionEqual channel angular pressingalloymagnesiumtetrazoliumthiazole derivativethiazolyl blueArticlebiomechanicscell viabilitycontrolled studycorrosioncrystallographyhumanhuman cellimmersionin vitro studyMG-63 cell lineparticle sizetensile strengthbiodegradable implantbone prosthesiscell survivalchemistrymaterials testingmechanical stressorthopedicsproceduresprostheses and orthosesprosthesis designradiation scatteringtumor cell lineAbsorbable ImplantsAlloysBone SubstitutesCell Line, TumorCell SurvivalCorrosionHumansMagnesiumMaterials TestingOrthopedicsProstheses and ImplantsProsthesis DesignScattering, RadiationStress, MechanicalTensile StrengthTetrazolium SaltsThiazoles