Harikrishna, N.Isloor, A.M.Kulal, K.AlObaid, A.Fun, H.-K.2026-02-052016New Journal of Chemistry, 2016, 40, 1, pp. 73-7611440546https://doi.org/10.1039/c5nj02237ahttps://idr.nitk.ac.in/handle/123456789/26163A new series of 1?-(4-chlorophenyl)-5-(substituted aryl)-3?-(substituted aryl)-3,4-dihydro-2H,1?H-[3,4?]bipyrazolyl derivatives (6a-e, 8a-e, 10a-e) have been synthesized, characterized and screened for antimicrobial and antitubercular activity. Among the synthesized compounds, the minimum inhibition concentration of 10e was found to be as low as 1.56 ?g ml-1 and that of 10c was 6.25 ?g ml-1 as compared to the standard anti-tb drugs pyrazinamide and streptomycin. © The Royal Society of Chemistry and the Centre National de la Recherche Scientifique 2016.1' (4 chlorophenyl) 5 (2,3 dihydrobenzofuran 5 yl) 3' phenyl 3,4 dihydro 2h,1h [3,4']bipyrazolyl1' (4 chlorophenyl) 5 (5 methylfuran 2 yl) 3' phenyl 3,4 dihydro 2h,1h [3,4']bipyrazolyl5 biphenyl 4 yl 1' (4 chlorophenyl) 3' phenyl 3,4 dihydro 2h,1h [3,4']bipyrazolylantiinfective agentpyrazinamidepyrazoline derivativestreptomycintuberculostatic agentunclassified drugantimicrobial activityantitubercular activityArticlecarbon nuclear magnetic resonancedrug activitydrug structuredrug synthesisminimum inhibitory concentrationpriority journalproton nuclear magnetic resonance