Ranganath, A.Shet, K.C.S.Vidyavathi, N.2020-03-312020-03-312007In Silico Biology, 2007, Vol.7, 2, pp.169-174https://idr.nitk.ac.in/handle/123456789/10936Structural Genomics initiatives are generating an increasing number of protein structures with very limited biochemical characterization. Characterization of a protein's function and understanding the specific nature of a protein's binding is a critical part of both protein engineering and structure-based drug discovery. The accurate detection of binding site in these protein structures can be valuable in determining its function. As shape plays a crucial role in bimolecular recognition and function, the development of shape analysis techniques is important for understanding protein structure-function relationships. This paper describes the use of the continuous wavelet transforms (CWT) for characterizing shape features of 3D protein structures. The goal is to explore the CWT as a multiscale tool to generate rotation- and translation-invariant shape features. 2007 IOS Press. All rights reserved.Article