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DC Field | Value | Language |
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dc.contributor.author | Nainegali B.S. | |
dc.contributor.author | Iyyaswami R. | |
dc.contributor.author | D Belur P. | |
dc.date.accessioned | 2021-05-05T10:27:47Z | - |
dc.date.available | 2021-05-05T10:27:47Z | - |
dc.date.issued | 2020 | |
dc.identifier.citation | Separation and Purification Technology Vol. 253 , , p. - | en_US |
dc.identifier.uri | https://doi.org/10.1016/j.seppur.2020.117520 | |
dc.identifier.uri | http://idr.nitk.ac.in/jspui/handle/123456789/15714 | - |
dc.description.abstract | The simultaneous extraction of anthocyanins (ACNs), garcinol (GL), isogarcinol (IGL) and hydroxycitric acid (HCA) from the rinds of Garcinia indica (GI) fruit and their partition behaviour in the aqueous two-phase system (ATPS) formed by 1-propanol-(NH4)2SO4 was investigated. The effect of different variables that govern the partition characteristics were studied and the amount of crude loaded into the ATPS, the concentration of 1-propanol and (NH4)2SO4 were found to be the significant variables. The Response Surface Methodology (RSM) was adopted to optimize the process variables through desirability based multi-response optimization for the partitioning of GL and IGL to the alcohol rich top phase and ACNs and HCA to the salt-rich bottom phase by considering the partitioning coefficients (K) and extraction efficiency of all the four bioactive components as responses. A ATPS consisting of 15.202% (w/w) 1-propanol, 10.242% (w/w) (NH4)2SO4 having the TLL of 28.505% (w/w) at a crude load of 25% (w/w) able to partition 97.39% GL (K = 370.770) and 92.38% IGL (K = 120.581) in the top phase and 99.19% ACNs (K = 0.080) and 99.83% HCA (K = 0.016) in the bottom phase with a purity higher than 99% by implementing secondary ATPS. © 2020 Elsevier B.V. | en_US |
dc.title | Partitioning of bio-active compounds from rinds of garcinia indica using aqueous two-phase system: Process evaluation and optimization | en_US |
dc.type | Article | en_US |
Appears in Collections: | 1. Journal Articles |
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