Please use this identifier to cite or link to this item: https://idr.nitk.ac.in/jspui/handle/123456789/13266
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dc.contributor.authorMalladi, S.
dc.contributor.authorIsloor, A.M.
dc.contributor.authorPeethambar, S.K.
dc.contributor.authorFun, H.K.
dc.date.accessioned2020-03-31T08:45:29Z-
dc.date.available2020-03-31T08:45:29Z-
dc.date.issued2013
dc.identifier.citationMedicinal Chemistry Research, 2013, Vol.22, 6, pp.2654-2664en_US
dc.identifier.urihttp://idr.nitk.ac.in/jspui/handle/123456789/13266-
dc.description.abstractNew (E)-1-aryl-3-(3-aryl-1-phenyl-1H-pyrazol-4-yl)prop-2-en-1-ones 6 (pyrazolic chalcones) were synthesized from Claisen-Schmidt reaction of 3-aryl-1-phenylpyrazol-4-carboxaldehydes 4 with several acetophenone derivatives 5. Subsequently, the cyclocondensation reaction of chalcones 6 with phenylhydrazine in acetic acid medium afforded the new 3-aryl-4-(3-aryl-4,5- dihydro-1H-pyrazol-5-yl)-1-phenyl-1H-pyrazoles 7. The synthesized compounds were characterized by spectral studies and evaluated for their in vitro antibacterial activity against three pathogenic bacterial strains, Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa, and in vitro antifungal activity against three pathogenic fungal strains Aspergillus flavus, Chrysosporium keratinophilum, and Candida albicans. 2012 Springer Science+Business Media New York.en_US
dc.titleSynthesis of new 3-aryl-4-(3-aryl-4,5-dihydro-1H-pyrazol-5-yl)-1-phenyl-1H- pyrazole derivatives as potential antimicrobial agentsen_US
dc.typeArticleen_US
Appears in Collections:1. Journal Articles

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