Please use this identifier to cite or link to this item:
|Title:||Novel chromeno [2,3-b]-pyrimidine derivatives as potential anti-microbial agents|
|Authors:||Sankappa, Rai, U.|
|Citation:||European Journal of Medicinal Chemistry, 2010, Vol.45, 6, pp.2695-2699|
|Abstract:||An efficient, microwave irradiated synthesis of novel chromeno[2,3-b]-pyrimidine derivatives was carried out. 2-Amino-3,4-dihydro-2H-chromene-3-carbonitrile was converted into imine using N,N-Dimethylacetaldehyde dimethylacetal to give the core intermediate, which was used for the preparation of chromenopyrimidine library, using acetic acid and different amine in microwave irradiation for 5 min. Structures of newly synthesized compounds were confirmed by spectral studies. Compound 6g was characterized by single crystal X-ray analysis. All the compounds were also screened for their anti-microbial activity. Few of the compounds are found to be potential antimicrobials. 2010 Elsevier Masson SAS. All rights reserved.|
|Appears in Collections:||1. Journal Articles|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.