4-(Morpholin-4-yl)-3-(trifluoro-meth-yl)-benzonitrile

Abstract

In the title benzonitrile compound, C <inf>12</inf>H <inf>11</inf>F <inf>3</inf>N <inf>2</inf>O, an intra-molecular C - H?F hydrogen bond generates an S(7) ring motif. The trifluoro-methyl group is disordered over two orientations with a refined occupancy ratio of 0.549 (16):0.451 (16). The morpholine ring adopts a chair conformation. The benzene ring and mean plane of the morpholine ring make a dihedral angle of 58.04 (10)° with each other. In the crystal, mol-ecules are connected by inter-molecular C - H?F and C - H?O inter-actions to form R 2 2(8) ring motifs. These inter-actions also link the mol-ecules into chains parallel to the [10[ direction. © Fun et al. 2011.