Synthesis of some new pyrazolines and isoxazoles carrying 4-methylthiophenyl moiety as potential analgesic and antiinflammatory agents

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dc.contributor.authorKarabasanagouda, T.
dc.contributor.authorVasudeva Adhikari, A.V.
dc.contributor.authorGirisha, M.
dc.date.accessioned2026-02-05T09:36:43Z
dc.date.issued2009
dc.description.abstractA series of new pyrazolines 3a-m and isoxazoies 4a-k have been synthesized from 4-acetylthioanisole, 1 with aryl aldehydes through ?, ?-unsaturated ketones. The structures of the newly synthesized compounds have been confirmed on the basis of elemental analysis and spectral studies. The newly synthesized title compounds have been tested for their analgesic and antiinflammatory activity. Some of the compounds exhibited encouraging results.
dc.identifier.citationIndian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2009, 48, 3, pp. 430-437
dc.identifier.issn3764699
dc.identifier.urihttps://idr.nitk.ac.in/handle/123456789/27654
dc.subject4-acetylthioanisole
dc.subjectAnalgesic
dc.subjectAnti-inflammatory activity
dc.subjectArylaldehydes
dc.subjectIsoxazoies
dc.subjectPropenones
dc.subjectPyrazolines
dc.titleSynthesis of some new pyrazolines and isoxazoles carrying 4-methylthiophenyl moiety as potential analgesic and antiinflammatory agents

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