Alcohol-based aqueous biphasic system applied to partition four different natural bioactive compounds from Garcinia indica Choisy
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Date
2021
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Journal Title
Journal ISSN
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Publisher
Bellwether Publishing, Ltd.
Abstract
An attempt was made to simultaneously partitioning Anthocyanins (ACN), Hydroxycitric acid (HCA), Garcinol (GL), and Isogarcinol (IGL) from fruit rinds of Garcinia indica using the 1-propanol and magnesium sulfate system. The influences of 1-propanol and magnesium sulfate concentration and Tie line Length (TLL) were investigated to obtain the optimal partitioning and recovery of GL and IGL into the top-phase and ACN and HCA to the bottom phase. The 25% w/w 1-propanol and 12% w/w magnesium sulfate system showed the maximum extraction efficiency for all the compounds. The purity and recovery were further improved by employing the second stage ATPS. © 2020 Taylor & Francis Group, LLC.
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Keywords
Sulfur compounds, 1-propanol, Aqueous biphasic system, Bioactive compounds, Extraction efficiencies, Garcinia indica, Hydroxycitric acids, Magnesium sulfate, Optimal partitioning, Magnesium compounds
Citation
Separation Science and Technology, 2021, 56, 11, pp. 1882-1898