A novel series of homoallylic amines as potential antimicrobials

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dc.contributor.authorRai, U.S.
dc.contributor.authorIsloor, A.M.
dc.contributor.authorShetty, P.
dc.contributor.authorIsloor, N.
dc.contributor.authorPadaki, M.
dc.contributor.authorFun, H.-K.
dc.date.accessioned2020-03-31T06:51:17Z
dc.date.available2020-03-31T06:51:17Z
dc.date.issued2012
dc.description.abstractAn efficient catalytic three-component reaction of aldehydes, amines, and allyltributylstannate has been successfully developed to produce homoallylic amines at 25 C, in excellent yields, in the presence of 1 mol% of trifluoroacetic acid an inexpensive and environmentally friendly catalyst. Newly synthesized compounds were confirmed by spectral studies. Compound 3o was characterized by single crystal X-ray analysis. All the compounds were also screened for their antimicrobial activity. Halogen-substituted compounds namely 3d, 3g, 3n, and 3o have showed excellent antibacterial activity. Springer Science+Business Media, LLC 2011.en_US
dc.identifier.citationMedicinal Chemistry Research, 2012, Vol.21, 7, pp.1090-1097en_US
dc.identifier.uri10.1007/s00044-011-9607-3
dc.identifier.urihttps://idr.nitk.ac.in/handle/123456789/9681
dc.titleA novel series of homoallylic amines as potential antimicrobialsen_US
dc.typeArticleen_US

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