Synthesis of functionalized benzo[1,3]dioxin-4-ones from salicylic acid and acetylenic esters and their direct amidation

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dc.contributor.authorBhaskaran, R.P.
dc.contributor.authorNayak, K.H.
dc.contributor.authorBabu, B.P.
dc.date.accessioned2026-02-05T09:26:57Z
dc.date.issued2021
dc.description.abstractDirect synthesis of 4H-benzo[d][1,3]dioxin-4-one derivatives from salicylic acids and acetylenic esters (both mono- and disubstituted) has been described. The reaction is mediated by CuI and NaHCO<inf>3</inf>in acetonitrile. Room temperature amidation of the synthesized 1,3-benzodioxinones with primary amines readily afforded the corresponding salicylamides in moderate to good yields. © The Royal Society of Chemistry 2021.
dc.identifier.citationRSC Advances, 2021, 11, 40, pp. 24570-24574
dc.identifier.urihttps://doi.org/10.1039/d1ra05032j
dc.identifier.urihttps://idr.nitk.ac.in/handle/123456789/23171
dc.publisherRoyal Society of Chemistry
dc.subjectAmines
dc.subjectCopper compounds
dc.subjectEsters
dc.subjectIodine compounds
dc.subjectOrganic pollutants
dc.subjectSodium compounds
dc.subjectAmidation
dc.subjectDirect synthesis
dc.subjectFunctionalized
dc.subjectPrimary amines
dc.subjectSalicylamides
dc.subjectSalicylic acid
dc.titleSynthesis of functionalized benzo[1,3]dioxin-4-ones from salicylic acid and acetylenic esters and their direct amidation

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