Metal-Free Synthesis of Pyrazoles and Chromenopyrazoles from Hydrazones and Acetylenic Esters

Abstract

An efficient, metal-free synthesis of pyrazoles and chromenopyrazoles from aldehyde hydrazones and acetylenic esters has been developed. A library of molecules with diverse functional groups has been synthesized using substituted hydrazones and alkynes, both symmetrical and unsymmetrical ones. The derivatives were isolated in moderate to good yields. © 2020 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim