Effective role of P2O5 on in-vitro bioactivity of soda lime phosphosilicate glasses

Abstract

In-vitro bio active properties have been studied on Sol-gel derived 58SiO<inf>2</inf>-33CaO-(5-X) Na<inf>2</inf>O-(4+X) P<inf>2</inf>O<inf>5</inf> (where X=0, 5) bio glass samples soaked for seven days in a simulated body fluid (SBF) solution. X-ray diffraction studies indicated the presence of Hydroxyl Apatite (HA) crystalline phase in the synthesized samples. The spherical shaped hydroxyl carbonated apatite (HCA) nuclei were observed under scanning electron microscope. The Fourier transform infrared (FTIR) and Raman spectroscopic analysis confirmed the presence of carbonates in the glass matrix. In particular, larger concentration of P<inf>2</inf>O<inf>5</inf> in the bioglass resulted in superior bioactivity compared to low concentration of P<inf>2</inf>O<inf>5.</inf> © 2017 Elsevier Ltd.