A catalyst- and solvent-free three-component reaction for the regioselective one-pot access to polyfunctionalized pyrroles
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Date
2013
Authors
Bhat, S.I.
Trivedi, D.R.
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Abstract
A facile method for the regioselective synthesis of tetrasubstituted pyrroles, from readily accessible 1,3-dicarbonyls, benzoin derivatives and ammonium acetate, has been developed. The one-pot three-component reactions were performed to afford tetrasubstituted pyrroles under solvent- and catalyst-free conditions. 2013 Elsevier Ltd. All rights reserved.
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Tetrahedron Letters, 2013, Vol.54, 41, pp.5577-5582