Hemocompatibility of Sulfuric Acid-Treated Metallocene Polyethylene and its Application in Reducing the Quantity of Medical Plastic Waste
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Date
2017
Journal Title
Journal ISSN
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Publisher
Taylor and Francis Inc. 325 Chestnut St, Suite 800 Philadelphia PA 19106
Abstract
The hazards of dumping medical plastics have created a huge demand to reduce the quantity of plastic usage without compromising its quality. The metallocene synthesized polyethylene is one such advent, however, its clinical usage is limited by the problem of hemocompatibility. This study investigates the effect of sulfuric acid-induced changes in metallocene polyethylene. Fourier transform infrared spectroscopy analysis illustrated the addition of OH and sulfonic acid group, which subsequently increased the wettability. An improvement in micro as well as nanosurface roughness was observed. Ultimately, the treated surfaces depicted delayed clotting time, adsorption of specific plasma proteins, reduced hemolysis, and resistance against platelet adhesion. © 2017 Taylor & Francis.
Description
Keywords
Adhesion, Biocompatibility, Fourier transform infrared spectroscopy, Functional polymers, Metals, Organometallics, Platelets, Proteins, Sulfuric acid, Surface properties, Surface treatment, Biocompatible polymer, Blood compatibility, Coagulation pathway, Metallocene polyethylene, Platelet adhesion, Protein adsorption, Sulfuric acid treatment, Polyethylenes
Citation
Polymer - Plastics Technology and Engineering, 2017, 56, 3, pp. 240-253