Metal free synthesis of 1-azaspiro[4.4]nonane-3-one system via reactions of nitrones with 1,1-disubstituted allenes
| dc.contributor.author | Amrutha, U. | |
| dc.contributor.author | Babu, B. | |
| dc.contributor.author | Prathapan, S. | |
| dc.date.accessioned | 2026-02-05T09:29:22Z | |
| dc.date.issued | 2019 | |
| dc.description.abstract | In the cycloaddition reaction between fluorenone N-aryl nitrones and 1,1-disubstituted allenes, the initially formed cycloadduct underwent facile [1,3] shift to give 1?-phenylspiro[fluorene-9,2?-pyrrolidin]-4?-ones. Although 1?-phenylspiro[fluorene-9,2?-pyrrolidin]-4?-ones are stable in solid state, a few of them underwent facile aerial oxidation in solution to give the corresponding 1?-phenylspiro[fluorene-9,2?-pyrrolidine]-4?,5?-diones in excellent overall yields. © 2019 Wiley Periodicals, Inc. | |
| dc.identifier.citation | Journal of Heterocyclic Chemistry, 2019, 56, 12, pp. 3236-3243 | |
| dc.identifier.issn | 0022152X | |
| dc.identifier.uri | https://doi.org/10.1002/jhet.3718 | |
| dc.identifier.uri | https://idr.nitk.ac.in/handle/123456789/24262 | |
| dc.publisher | HeteroCorporation support@jhetchem.com | |
| dc.subject | article | |
| dc.subject | cycloaddition | |
| dc.subject | oxidation | |
| dc.subject | solid state | |
| dc.subject | synthesis | |
| dc.title | Metal free synthesis of 1-azaspiro[4.4]nonane-3-one system via reactions of nitrones with 1,1-disubstituted allenes |