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Item Corrigendum to Novel N-substituted-5-phenyl-1H-pyrazole-4-ethyl carboxylates as potential NLO materials [Arab. J. Chem. (6) (2013) 97-102](2013) Chandrakantha B.; Isloor, A.M.; Sridharan K.; Philip R.; Shetty P.; Padaki M.; Fun H.-K.[No abstract available]Item Corrigendum to In vivo anticancer and histopathology studies of Schiff bases on Ehrlich ascitic carcinoma cells [Arabian Journal of Chemistry 6(1) (2013) 25-33](2013) Sunil D.; Isloor, A.M.; Shetty P.; Nayak P.G.; Pai K.S.R.; Fun H.-K.[No abstract available]Item Carbon nanotube- and graphene-based advanced membrane materials for desalination(2017) Hebbar R.S.; Isloor, A.M.; Inamuddin; Asiri A.M.The development of membrane-based desalination and water purification technologies offers new alternatives to meet the global freshwater demand. Rapid advancement in carbon nanotube-based and graphene-based nanomaterials has drawn the attention of scientific investigators on various desalination technologies. These nanomaterials indeed offer advantageous structure, size, shape, porosity and mass transport behavior for membrane separation process. This article reviews theoretical and experimental investigations of carbon nanotube- and graphene-based composite materials for desalination. Special attention is given to the simulation of molecular transport through these materials. Further, recent advances in the application of functionalization of carbon nanotube- and graphene-based materials for salt rejection and hydraulic permeation properties are discussed. © 2017, Springer International Publishing AG.Item A review on RO membrane technology: Developments and challenges(2015) Shenvi S.S.; Isloor, A.M.; Ismail A.F.Reverse osmosis (RO) based desalination is one of the most important and widely recognized technologies for production of fresh water from saline water. Since its conception and initiation, a significant development has been witnessed in this technology w.r.t. materials, synthesis techniques, modification and modules over the last few decades. The working of a RO plant inclusive of the pretreatment and post-treatment procedures has been briefly discussed in the article. The main objective of this review is to highlight the historical milestones achieved in RO technology in terms of membrane performance, the developments seen over the last few years and the challenges perceived. The material properties of the membrane dominate the performance of a RO process. The emergence of nano-technology and biomimetic RO membranes as the futuristic tools is capable of revolutionizing the entire RO process. Hence the development of nano-structured membranes involving thin film nano-composite membranes, carbon-nanotube membranes and aquaporin-based membranes has been focussed in detail. The problems associated with a RO process such as scaling, brine disposal and boron removal are briefed and the measures adopted to address the same have been discussed. © 2014 Elsevier B.V.Item Item Chitosan and its derivatives as potential materials for membrane technology(2015) Kumar R.; Isloor, A.M.Chitosan (CS), a biomaterial obtained via alkaline N-deacetylation of chitin, has recently attracted much attention from scientists across the globe. After cellulose, it is the second highest naturally occurring polymer on earth. It shows many excellent biological properties such as nontoxicity, biodegradability, antimicrobial activity, and immunological activity. As a membrane material, it has got excellent film-forming nature and hydrophilic in nature. Although the polymer backbone consists of hydrophilic functional groups, CS is normally insoluble in water and most of the common organic solvents. Chemical modification of CS is the best method to enhance its solubility at neutral pH or in organic solvents. So the obtained derivatives have got vast applications in the biomedical field as well as membrane technology. © 2015 by Taylor & Francis Group, LLC.Item Contact Angle Measurements(2017) Hebbar R.S.; Isloor, A.M.; Ismail A.F.Contact angle has been an important parameter to determine the wetting ability of the polymer membrane surface. Contact angle has gained interest in surface science in regards to its fundamental aspects and application point of view. This chapter will give an insight into fundamentals of contact angle including the theoretical backgrounds, brief history, and importance of contact angle. The various factors that affect the contact angle measurement will also be discussed. The chapter will also present contact angle hysteresis phenomena, comprising of advancing and receding contact angles along with the manifestations of contact angle hysteresis. The chapter will highlight the various methods and techniques available for the measurement of contact angle along with the comprehensive description of the methods. The chapter also covers the application contact angle on surface characterization, permeation, and antifouling nature of the membrane. © 2017 Elsevier B.V. All rights reserved.Item The effect of glycine betaine additive on the PPSU/PSF ultrafiltration membrane performance(2016) Moideen, K, I.; Isloor, A.M.; Garudachari, B.; Ismail, A.F.A series of new ultrafiltration (UF) membranes were prepared by blending polyphenylsulfone and polysulfone with glycine betaine (GB) and polyethylene glycol-1000 (PEG-1000) as additive. GB of varying concentrations (0 2 wt.%) were dissolved in N-Methyl-2-pyrrolidone to prepare the membranes by phase inversion method. The membranes were characterized by Scanning Electron Microscope and dispersive X-ray analysis to study the asymmetric nature of membranes and the retention of GB in membranes, respectively. The stability tests were conducted to study the stability of additives in the membranes. The membrane hydrophilicity was determined by contact angle, porosity, water uptake, and permeability studies. The addition of GB additives enhanced the membrane performance like permeability, antifouling property, and heavy metal rejection. Also, the antifouling property improved with the addition of GB. The antifouling nature was calculated by flux recovery ratio, reversible and irreversible fouling. Polymer-enhanced UF of heavy metals like Pb2+ and Cd2+ was performed and rejection of 80.23 and 71.45%, respectively, was exhibited by the GB 1 membrane with agreeable permeability and antifouling property. 2016 Balaban Desalination Publications. All rights reserved.Item Synthesis, characterization, antioxidant, and anticancer studies of 6-[3-(4-chlorophenyl)-1H-pyrazol-4-yl]-3-[(2-naphthyloxy) methyl][1,2,4] triazolo[3,4-b][1,3,4]thiadiazole in HepG2 cell lines(2011) Sunil, D.; Isloor, A.M.; Shetty, P.; Satyamoorthy, K.; Prasad, A.S.B.Triazolo- thiadiazoles exhibit a variety of pharmacological properties, due to their cytotoxicity. In continuation of a previous study on triazolo-thiadiazoles, the authors have synthesized a new thiadiazole, 6-[3-(4-chlorophenyl)- 1-H-pyrazol-4-yl]-3-[(2-naphthyloxy)methyl] [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole (CPNT), which was further characterized by advanced spectral techniques and elemental analysis. The compound exhibited a dose-dependent cytotoxic effect on hepatocellular carcinoma cell line, HepG2 with very low IC50 value of 0.8 ?g/ml in 24 h when compared with standard drug, doxorubicin. Incorporation of [3H] thymidine in conjunction with cell cycle analysis suggested that CPNT inhibited the growth of HepG2 cells. Flow cytometric studies revealed more percentage of cells in subG1 phase, indicating apoptosis, which was further confirmed through chromatin condensation studies by Hoechst staining. In vitro antioxidant activity of CPNT was determined by DPPH and ABTS free radical scavenging assays which revealed increasing scavenging activity with increasing concentration of the compound when compared with reference ascorbic acid. Springer Science+Business Media, LLC 2010.Item Synthesis, characterization, anticancer, and antioxidant activity of some new thiazolidin-4-ones in MCF-7 cells(2013) Isloor, A.M.; Sunil, D.; Shetty, P.; Malladi, S.; Pai, K.S.R.; Maliyakkl, N.There are limited studies centring on the potential of thiazolidin-4-ones as anticancer agents. In this study, a new series of 2-(3-substituted-1H- pyrazol-4-yl)-3-(3-substituted-5-sulfanyl-1,2,4-triazol-4-yl)-1, 3-thiazolidin-4-one (4a-o) have been synthesized by cyclo-condensation reaction of 5-substituted-4-[(3-substituted-1H-pyrazol-4-ylmethylidene)amino]-2H-1,2,4- triazole-3-thione (3a-o) and thioglycolic acid. The structures of all the synthesized compounds were confirmed by elemental analysis, spectral techniques like IR, 1H NMR, and mass spectroscopy. Few compounds exhibited dose-dependent cytotoxic effect in MTT assay in human breast cancer (MCF-7) cells. Apoptotic degradation of DNA due to action of potent thiazolidin-4-ones was analysed by agarose gel electrophoresis and visualized by ethidium bromide staining (comet assay). A concentration-dependent increase in tail length and olive tail moment was observed when treated with thiazolidin-4-ones. In vitro antioxidant studies like DPPH and ABTS-free radical scavenging assays-indicated moderate activity of thiazolidin-4-ones. 2012 Springer Science+Business Media, LLC.