Faculty Publications
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Item Analysis of cortical rhythms in intracranial EEG by temporal difference operators during epileptic seizures(Elsevier Ltd, 2016) Malali, A.; Chaitanya, G.; Gowda, S.; Majumdar, K.Brain oscillations have traditionally been studied by time-frequency analysis of the electrophysiological signals. In this work we demonstrated the usefulness of two nonlinear combinations of differential operators on intracranial EEG (iEEG) recordings to study abnormal oscillations in human brain during intractable focal epileptic seizures. Each one dimensional time domain signal was visualized as the trajectory of a particle moving in a force field with one degree of freedom. Modeling of the temporal difference operators to be applied on the signals was inspired by the principles of classical Newtonian mechanics. Efficiency of one of the nonlinear combinations of the operators in distinguishing the seizure part from the background signal and the artifacts was established, particularly when the seizure duration was long. The resultant automatic detection algorithm is linear time executable and detects a seizure with an average delay of 5.02 s after the electrographic onset, with a mean 0.05/h false positive rate and 94% detection accuracy. The area under the ROC curve was 0.959. Another nonlinear combination of differential operators detects spikes (peaks) and inverted spikes (troughs) in a signal irrespective of their shape and size. It was shown that in a majority of the cases simultaneous occurrence of all the spikes and inverted spikes across the focal channels was more after the seizure offset than during the seizure, where the duration after the offset was taken equal to the duration of the seizure. It has been explained in terms of GABAergic inhibition of seizure termination. © 2016 Elsevier Ltd. All rights reserved.Item Experimental investigation on the suitability of flexible pressure sensor for wrist pulse measurement(Springer Verlag service@springer.de, 2019) Sukesh Rao, S.; Rao, R.Pulse examination at the radial artery of the wrist is a most apparent diagnosis technique. Wrist pulse carries rich information about the cardiovascular system of human body. An investigation is made here to suggest suitable flexible type of thin film pressure sensor to measure the wrist pulse as per Ayurvedic medicine system. Primary objective of this work is to suggest a sensor which exhibits optimum spatial features and SNR values. Force Sensing Resistor (FSR), piezoresistive and piezoelectric thin film sensors are considered under this study. Piezoelectric sensor shows good performance in the quality of the pulse with 22 dB SNR. Further experimentation is conducted to find out transmissivity, repeatability and susceptibility to motion artifact. Trasnsmissivities of 0.91, 0.68 and 0.64 are obtained for piezoelectric, piezoresistive and FSR sensors respectively. Piezoresistive and FSR show repeatability error of ±8% and ± 7% while measuring pulse amplitude under standard force. Noise due to motion artifact for each type of sensors are recorded and compared with the standard Gaussian distribution function with the help of histogram. Collectively, piezoelectric sensor exhibits good spatial features, high transmissivity and comparatively low susceptibility to motion artifact. © 2018, IUPESM and Springer-Verlag GmbH Germany, part of Springer Nature.Item Automatic detection and localization of Focal Cortical Dysplasia lesions in MRI using fully convolutional neural network(Elsevier Ltd, 2019) Bijay Dev, K.M.; Pawan, P.S.; Niyas, S.; Vinayagamani, S.; Kesavadas, C.; Rajan, J.Focal cortical dysplasia (FCD) is the leading cause of drug-resistant epilepsy in both children and adults. At present, the only therapeutic approach in patients with drug-resistant epilepsy is surgery. Hence, the quantification of FCD via non-invasive imaging techniques helps physicians to decide on surgical interventions. The properties like non-invasiveness and capability to produce high-resolution images makes magnetic resonance imaging an ideal tool for detecting the FCD to an extent. The FCD lesions vary in size, shape, and location for different patients and make the manual detection time consuming and sensitive to the experience of the observer. Automatic segmentation of FCD lesions is challenging due to the difference in signal strength in images acquired with different machines, noise, and other kinds of distortions such as motion artifacts. Most of the methods proposed in the literature use conventional machine learning and image processing techniques in which their accuracy relies on the trained features. Hence, feature extraction should be done more precisely which requires human expertise. The ability to learn the appropriate features/representations from the training data without any human interventions makes the convolutional neural network (CNN) the suitable method for addressing these drawbacks. As far as we are aware, this work is the first one to use a CNN based model to solve the aforementioned problem using only MRI FLAIR images. We customized the popular U-Net architecture and trained the proposed model from scratch (using MRI images acquired with 1.5T and 3T scanners). FCD detection rate (recall) of the proposed model is 82.5 (33/40 patients detected correctly). © 2019Item Detection of arrhythmia from electrocardiogram signals using a novel gaussian assisted signal smoothing and pattern recognition(Elsevier Ltd, 2022) Chandrasekar, A.; Shekar, D.D.; Hiremath, A.C.; Chemmangat, K.The electrocardiogram is a widely used measurement for individual heart conditions, and much effort has been put into automatic arrhythmia diagnosis using machine learning. However, the classification performance is hampered by the use of less representative data in conjunction with traditional machine learning models. This paper proposes a novel algorithm for pre-processing raw Electrocardiogram signals via Gaussian Assisted Signal Smoothing. In this method, the ECG signal is modeled as a low pass component and a weighted sum of Gaussians. The Gaussians are used to model the peak characteristics of the signal, effectively preserving its structure and morphology while eliminating the noise, which is evident by the enhanced peak signal-to-noise ratio of the GASS signal. The R peaks obtained from the Pan Tompkins algorithm are used to extract the heartbeats from the filtered signal using a windowing technique. A cascaded combination of a Convolutional Neural Network and a Quadratic Support Vector Machine is then used to classify the heartbeats. The CNN model has 131,661 parameters, making it much lighter than previously reported works. The MIT-BIH Arrhythmia Database was used for our experiments. Across eleven classes, our results reveal that the model has an accuracy of 97.63% and an average F1 score of 0.9263. In contrast, previous works have primarily focused on a one vs. all or a five-class classification. From a signal processing standpoint, the proposed method offers a promising solution for Signal Filtering and Arrhythmia Classification. © 2021 Elsevier LtdItem A novel procedure to automate the removal of PLI and motion artifacts using mode decomposition to enhance pattern recognition of sEMG signals for myoelectric control of prosthesis(Institute of Physics, 2024) Kumar Koppolu, P.; Chemmangat, K.Hand Movement Recognition (HMR) with sEMG is crucial for artificial hand prostheses. HMR performance mostly depends on the feature information that is fed to the classifiers. However, sEMG often captures noise like power line interference (PLI) and motion artifacts. This may extract redundant and insignificant feature information, which can degrade HMR performance and increase computational complexity. This study aims to address these issues by proposing a novel procedure for automatically removing PLI and motion artifacts from experimental sEMG signals. This will make it possible to extract better features from the signal and improve the categorization of various hand movements. Empirical mode decomposition and energy entropy thresholding are utilized to select relevant mode components for artifact removal. Time domain features are then used to train classifiers (kNN, LDA, SVM) for hand movement categorization, achieving average accuracies of 92.36%, 93.63%, and 98.12%, respectively, across subjects. Additionally, muscle contraction efforts are classified into low, medium, and high categories using this technique. Validation is performed on data from ten subjects performing eight hand movement classes and three muscle contraction efforts with three surface electrode channels. Results indicate that the proposed preprocessing improves average accuracy by 9.55% with the SVM classifier, significantly reducing computational time. © 2024 IOP Publishing Ltd. 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