Faculty Publications
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Item The heart rate is a non-stationary signal, and its variation can contain indicators of current disease or warnings about impending cardiac diseases. The indicators can be present at all times or can occur at random, during certain intervals of the day. However, to study and pinpoint abnormalities in large quantities of data collected over several hours is strenuous and time consuming. Hence, heart rate variation measurement (instantaneous heart rate against time) has become a popular, non-invasive tool for assessing the autonomic nervous system. Computer-based analytical tools for the in-depth study and classification of data over day-long intervals can be very useful in diagnostics. The paper deals with the classification of cardiac rhythms using an artificial neural network and fuzzy relationships. The results indicate a high level of efficacy of the tools used, with an accuracy level of 80-85%. © IFMBE: 2004.(Classification of cardiac abnormalities using heart rate signals) Acharya, A.U.; Kumar, A.; Subbanna Bhat, P.; Lim, C.M.; Iyengar, S.S.; Kannathal, N.; Krishnan, S.M.2004Item Optimization and analysis of nickel adsorption on microwave irradiated rice husk using response surface methodology (RSM)(2009) Ganesapillai, M.G.; Iyyaswami, I.; Helen Kalavathy, M.H.; Murugesan, T.; Miranda, L.R.Background: The removal of heavy metals using adsorption techniques with low cost biosorbents is being extensively investigated. The improved adsorption is essentially due to the pores present in the adsorbent. One way of improving the porosity of the material is by irradiation of the precursor using microwaves. In the present study, the adsorption characteristics of nickel onto microwave-irradiated rice husks were studied and the process variables were optimized through response surface methodology (RSM). Result: The adsorption of nickel onto microwave-irradiated rice husk (MIRH) was found to be better than that of the raw rice husk (RRH). The kinetics of the adsorption of Ni(II) from aqueous solution onto MIRH was found to follow a pseudo-second-order model. Thermodynamic parameters such as standard Gibbs free energy (?G°), standard enthalpy (?H°), and standard entropy (?S°)were also evaluated. The thermodynamics of Ni(II) adsorption onto MIRH indicates that it is spontaneous and endothermic in nature. The response surface methodology (RSM) was employed to optimize the design parameters for the present process. Conclusion: Microwave-irradiated rice husk was found to be a suitable adsorbent for the removal of nickel(II) ions from aqueous solutions. The adsorption capacity of the rice husk was found to be 1.17 mg g-1. The optimized parameters for the current process were found as follows: adsorbent loading 2.8 g (100 mL)-1; Initial adsorbate concentration 6 mg L-1; adsorption time 210 min.; and adsorption temperature 35°C. © 2008 Society of Chemical Industry.Item A study about evolutionary and non-evolutionary segmentation techniques on hand radiographs for bone age assessment(Elsevier Ltd, 2017) Simu, S.; Lal, S.In this paper, a study and performance comparison of various evolutionary and non-evolutionary segmentation techniques on digital hand radiographs for bone age assessment is presented. The segmented hand bones are of vital importance in process of automated bone age assessment (ABAA). Bone age assessment is a technique of checking the skeletal development and detecting growth disorder in a person. However, it is very difficult to segment out the bone from the soft tissue. The problem arises from overlapping pixel intensities between bone region and soft tissue region and also between soft tissue region and background. Thus there is a requirement for a robust segmentation technique for hand bone segmentation. Taking this into consideration we make a comparison between non-evolutionary and evolutionary segmentation algorithms implemented on hand radiographs to recognize bone borders and shapes. The simulation and experimental results demonstrate that multiplicative intrinsic component optimization (MICO) algorithm provides better results as compared to other existing evolutionary and non-evolutionary algorithms. © 2016 Elsevier LtdItem A novel pre-processing procedure for enhanced feature extraction and characterization of electromyogram signals(Elsevier Ltd, 2018) Powar, O.S.; Chemmangat, K.; Figarado, S.In the analysis of electromyogram signals, the challenge lies in the suppression of noise associated with the measurement and signal conditioning. The main aim of this paper is to present a novel pre-processing step, namely Minimum Entropy Deconvolution Adjusted (MEDA), to enhance the signal for feature extraction resulting in better characterization of different upper limb motions. MEDA method is based on finding the set of filter coefficients that recover the output signal with maximum value of kurtosis while minimizing the low kurtosis noise components. The proposed method has been validated on surface electromyogram dataset collected from seven subjects performing eight classes of hand movements (wrist flexion, wrist radial deviation, hand close, tripod, wrist extension, wrist ulnar deviation, cylindrical and key grip) with only two pairs of electrodes recorded from flexor carpi radialis and extensor carpi radialis on the forearm. The performance of the MEDA has been compared across four classifiers namely J-48, k-nearest neighbours (KNN), Naives Bayes and Linear Discriminant Analysis (LDA) attaining the classification accuracy of 85.3 ± 4%, 85.67 ± 5%, 76 ± 6% and 91.2 ± 2% respectively. Practical results demonstrate the feasibility of the approach with mean percentage increase in classification accuracy of 20.5%, without significant increase in computational time across seven subjects demonstrating the significance of MEDA in classification. © 2018 Elsevier LtdItem A Noise Reduction Technique Based on Nonlinear Kernel Function for Heart Sound Analysis(Institute of Electrical and Electronics Engineers Inc., 2018) Mondal, A.; Saxena, I.; Tang, H.; Banerjee, P.The main difficulty encountered in interpretation of cardiac sound is interference of noise. The contaminated noise obscures the relevant information, which are useful for recognition of heart diseases. The unwanted signals are produced mainly by lungs and surrounding environment. In this paper, a novel heart sound denoising technique has been introduced based on a combined framework of wavelet packet transform and singular value decomposition (SVD). The most informative node of the wavelet tree is selected on the criteria of mutual information measurement. Next, the coefficient corresponding to the selected node is processed by the SVD technique to suppress noisy component from heart sound signal. To justify the efficacy of the proposed technique, several experiments have been conducted with heart sound dataset, including normal and pathological cases at different signal to noise ratios. The significance of the method is validated by statistical analysis of the results. The biological information preserved in denoised heart sound signal is evaluated by the k-means clustering algorithm. The overall results show that the proposed method is superior than the baseline methods. © 2013 IEEE.Item Calorespirometric investigation of Streptococcus zooepidemicus metabolism: Thermodynamics of anabolic payload contribution by growth and hyaluronic acid synthesis(Elsevier B.V., 2019) Mohan, N.; Allampalli, S.S.; Achar, A.; Swaminathan, N.; Sivaprakasam, S.Thermodynamic analysis of carbon flux competing for pathways of S. zooepidemicus in the production of catabolic (Lactic acid) and anabolic (Biomass and Hyaluronic Acid) products is investigated to assimilate the thermodynamic advantages of biopolymer production. Calorespirometry was employed to fingerprint the on-going HA production process and to predict reliable estimation of catabolic and anabolic product yields. This study accomplished the HA production at different initial glucose concentrations, S0 (10–60 g/L) to subject different levels of anabolic burden on S. zooepidemicus. Anabolic payload comprising Biomass and HA yields showed a concomitant decrease with respect to the increased concentration of S0. Chemical entropy exported over the cell surface in the form of LA production exhibited an increasing trend at different levels of glucose, thus reducing the total yields of biomass and HA. Thermodynamically anabolic load contributed by biomass and HA production found to have minor influence over the driving force of S. zooepidemicus metabolism due to their lower yields. The entropy contribution to the overall driving force is significant (T?SX= [Formula presented] ?rGX) at the higher biomass yields. This study allows the prediction of optimum biomass yield towards enhanced HA production and addresses the scope of ‘thermodynamic constraints’ application in real-time process monitoring and control using data reconciliation strategy in the near future. © 2019 Elsevier B.V.Item Distributed video coding based on classification of frequency bands with block texture conditioned key frame encoder for wireless capsule endoscopy(Elsevier Ltd, 2020) Sushma, B.; Aparna., P.Wireless capsule endoscopy (WCE) has provided remarkable improvement in diagnosing gastrointestinal disorders by scanning the entire digestive tract. The system still need refinement, to upgrade the quality of images, frame rate and battery life. The principal component of the system that can address these issues is low complexity video compressor. Motivated by low computational complexity requirements of WCE video encoding, this paper presents a distributed video coding framework based on frequency bands classification. The lower frequency bands are used to generate good quality side information (SI) as they exhibit high temporal correlation. This reduces the complexity of hash generation at the encoder, thus eliminating the latency in SI creation. Apart from this, SI creation involves only a simple block search and doesn't depend on Wyner–Ziv (WZ) bands. Also different approach for distributed coding of sub-sampled chroma components of WZ frame is proposed. Low complexity JPEG based key frame encoding is proposed that take advantage of WCE image textural properties to reduce the complexity of encoding smooth blocks by 81% at the quantization and encoding stage. Other novel features include use of discrete Tchebichef transform (DTT), Golomb–Rice code for entropy coding. Performance evaluation shows that the proposed method achieves 60% improvement in compression over Motion JPEG with low computational complexity. © 2020 Elsevier LtdItem Automatic selection of IMFs to denoise the sEMG signals using EMD(Elsevier Ltd, 2023) Koppolu, P.K.; Chemmangat, K.Surface Electromyography (sEMG) signals are muscle activation signals, which has applications in muscle diagnosis, rehabilitation, prosthetics, and speech etc. However, they are known to be affected by noises such as Power Line Interference (PLI), motion artifacts etc. Currently, Empirical Mode Decomposition (EMD) and its modifications such as Ensemble EMD (EEMD), and Complementary EEMD (CEEMD) are used to decompose EMG into a series of Intrinsic Mode Functions (IMFs). The denoised EMG can be obtained from the selected IMFs. Statistical methods are used to select the signal dominant IMFs to reconstruct the denoised signal. In this work, a novel procedure is proposed to automatically separate noisy IMFs from the original sEMG signal. For this purpose, Permutation Entropy (PE) is employed in EEMD sifting process called Partly EEMD (PEEMD), to separate the noisy IMFs from the original sEMG signal according to the preset PE threshold. PEEMD decomposes the original signal into various modes according to a preset PE threshold and the denoised signal is reconstructed from resultant IMFs. The PEEMD denoising procedure is applied on the experimental sEMG data collected from eight subjects, that include six various upper limb movement classes. The proposed denoising procedure achieved an improved denoising performance in comparison with EMD, EEMD, and CEEMD. An alternate measure called Sample Entropy (SE) is also used in place of PE, for the automated sifting process as a comparison. Signal to Noise Ratio (SNR), Root Mean Square Error (RMSE), and Reconstruction Error (RE) parameters are used to evaluate the denoising performance. The results, averaged across eight subjects, demonstrate that the proposed denoising procedure outperforms the state-of-the-art EMD techniques in terms of these performance measures on the experimentally collected sEMG data samples. © 2023 Elsevier LtdItem A novel procedure to automate the removal of PLI and motion artifacts using mode decomposition to enhance pattern recognition of sEMG signals for myoelectric control of prosthesis(Institute of Physics, 2024) Kumar Koppolu, P.; Chemmangat, K.Hand Movement Recognition (HMR) with sEMG is crucial for artificial hand prostheses. HMR performance mostly depends on the feature information that is fed to the classifiers. However, sEMG often captures noise like power line interference (PLI) and motion artifacts. This may extract redundant and insignificant feature information, which can degrade HMR performance and increase computational complexity. This study aims to address these issues by proposing a novel procedure for automatically removing PLI and motion artifacts from experimental sEMG signals. This will make it possible to extract better features from the signal and improve the categorization of various hand movements. Empirical mode decomposition and energy entropy thresholding are utilized to select relevant mode components for artifact removal. Time domain features are then used to train classifiers (kNN, LDA, SVM) for hand movement categorization, achieving average accuracies of 92.36%, 93.63%, and 98.12%, respectively, across subjects. Additionally, muscle contraction efforts are classified into low, medium, and high categories using this technique. Validation is performed on data from ten subjects performing eight hand movement classes and three muscle contraction efforts with three surface electrode channels. Results indicate that the proposed preprocessing improves average accuracy by 9.55% with the SVM classifier, significantly reducing computational time. © 2024 IOP Publishing Ltd. All rights, including for text and data mining, AI training, and similar technologies, are reserved.Item The use of cloud based machine learning to predict outcome in intracerebral haemorrhage without explicit programming expertise(Springer Science and Business Media Deutschland GmbH, 2024) Hegde, A.; Vijayasenan, D.; Mandava, P.; Menon, G.Machine Learning (ML) techniques require novel computer programming skills along with clinical domain knowledge to produce a useful model. We demonstrate the use of a cloud-based ML tool that does not require any programming expertise to develop, validate and deploy a prognostic model for Intracerebral Haemorrhage (ICH). The data of patients admitted with Spontaneous Intracerebral haemorrhage from January 2015 to December 2019 was accessed from our prospectively maintained hospital stroke registry. 80% of the dataset was used for training, 10% for validation, and 10% for testing. Seventeen input variables were used to predict the dichotomized outcomes (Good outcome mRS 0–3/ Bad outcome mRS 4–6), using machine learning (ML) and logistic regression (LR) models. The two different approaches were evaluated using Area Under the Curve (AUC) for Receiver Operating Characteristic (ROC), Precision recall and accuracy. Our data set comprised of a cohort of 1000 patients. The data was split 8:1 for training & testing respectively. The AUC ROC of the ML model was 0.86 with an accuracy of 75.7%. With LR AUC ROC was 0.74 with an accuracy of 73.8%. Feature importance chart showed that Glasgow coma score (GCS) at presentation had the highest relative importance, followed by hematoma volume and age in both approaches. Machine learning models perform better when compared to logistic regression. Models can be developed by clinicians possessing domain expertise and no programming experience using cloud based tools. The models so developed lend themselves to be incorporated into clinical workflow. © The Author(s) 2024.