Faculty Publications

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    Simulation of Hemodynamics Phenomenon Using Computational Fluid Dynamics for Enhanced Diagnostics and Prognosis
    (Institute of Electrical and Electronics Engineers Inc., 2016) Hegde, S.S.; Deb, A.; Nagesh, S.
    Computational bio-mechanics is developing rapidly as a non-invasive tool to assist the medical fraternity to help both diagnosis and prognosis of human body related issues such as injuries, cardio-vascular dysfunction, atherosclerotic plaque etc. Any system that would help either assist diagnosis prognosis would be a boon to the doctors and medical society in general. Some work also has been done in the area related to the use of computational fluid mechanics to understand the flow of blood through the human body, an area of hemodynamics. Since cardio-vascular diseases are one of the main causes of loss of life, understanding of the blood flow with and without constraints (such as blockages), providing alternate methods of prognosis and further solutions to take care of issues related to blood flow would help save valuable life of such patients. This work attempts to use computational fluid dynamics (CFD) to solve specific problems related to hemodynamics. In particular mathematical modeling of the blood flow in arteries in the presence of successive blockages has been analyzed using CFD. Also considered is the effect of increase in Reynolds number on wall shear stress values. Also, the concept of fluid structure interaction has been used during analysis. © 2015 IEEE.
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    Computational fluid dynamic approach to understand the effect of increasing blockage on wall shear stress and region of rupture in arteries blocked by arthesclerotic plaque
    (UK Simulation Society Clifton Lane Nottingham NG11 8NS, 2016) Hegde, S.S.; Deb, A.; Nagesh, S.
    Computational bio-mechanics is developing rapidly as a non-invasive tool to assist the medical fraternity to help in both diagnosis and prognosis of human body related issues such as injuries, cardio-vascular dysfunction, atherosclerotic plaque etc. Any system that would help either properly diagnose such problems or assist prognosis would be a boon to the doctors and medical society in general. This project is an attempt to use numerical analysis techniques; in particular, computational fluid dynamics (CFD) to solve hemodynamics related problems. The mathematical modeling of the blood flow in arteries in the presence of successive blockages has been analyzed using CFD technique. Different cases of blockages in terms of percentages have been modeled to study the effect of blockage on wall shear stress values and also the effect of increase in Reynolds number on wall shear stress values. The concept of fluid structure interaction (FSI) has been used to study the effect of increasing von Mises stress on arteries and to determine the region of rupture in arteries. The simulation results are validated using in vivo measurement data from existing literature. © 2016, UK Simulation Society. All rights reserved.
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    Computational investigations on the hemodynamic performance of a new swirl generator in bifurcated arteries
    (Taylor and Francis Ltd. michael.wagreich@univie.ac.at, 2019) Prashantha, B.; Anish, S.
    Hemodynamic behaviour of blood in the bifurcated arteries are closely related to the development of cardiovascular disease. The secondary flows generated at the bifurcation zone promotes the deposition of atherogenic particles on the outer walls. The present study aims at suppressing the development of atherosclerosis plaque by inducing helical flow structure in the arterial passage. To realize this objective a novel swirl generator (stent like structure with an internal groove) has been developed to induce helicity in the bifurcated passage. The functional requirement of the swirl generator is to minimize the relative residence time (RRT) of the fluid layer near the endothelial wall without generating any additional pressure drop. Different configurations of the swirl generator have been tested computationally using large eddy simulation (LES) model. It is observed that the induced helical flow redistributes the kinetic energy from the centre to the periphery. A single rib swirl flow generator proximal to the stent treated passage can generate sufficient helicity to bring down the RRT by 36% without generating any additional pressure drop. The swirl flow adds azimuthal instability which increase vortex formations in the passage. The induced helical flow in the domain provokes more linked vortices, which may act as self-cleaning mechanism to the arterial wall. © 2018, © 2019 Informa UK Limited, trading as Taylor & Francis Group.