Faculty Publications

Permanent URI for this communityhttps://idr.nitk.ac.in/handle/123456789/18736

Publications by NITK Faculty

Browse

Has files: NoSubject: search.filters.subject.Antimicrobial agents

Search Results

Now showing 1 - 3 of 3
  • No Thumbnail Available
    Item
    Substituted quinoline derivatives as potent biological agents
    (Trans Tech Publications Ltd ttp@transtec.ch, 2014) Garudacharia, B.; Isloora, A.M.
    Quinoline derivatives are the most promising class of active pharmaceutical agents compared with other heterocyclic compounds. Biological activity profile of quinoline can easily be controlled by introducing some active pharmacophore to the core ring. This chapter deals with the synthesis of quinoline derivatives and its biological activity. The enhancement of biological activity by incorporation of active functional group and effect of these functional groups were explained briefly. Main focus is given to the synthesis of different substituted quinoline derivatives for biological application with respect to the position on the quinoline core ring and modification of quinoline ring. © (2014) Trans Tech Publications, Switzerland.
  • No Thumbnail Available
    Item
    Synthesis and biological evaluation of newer analogues of 2,5-disubstituted 1,3,4-oxadiazole containing pyrazole moiety as antimicrobial agents
    (Elsevier B.V., 2014) Malladi, S.; Isloor, A.M.; Peethambar, S.K.; Fun, H.-K.
    A series of 2,5-disubstituted-1,3,4-oxadiazole derivatives bearing pyrazole moiety were synthesized by reacting various substituted pyrazole-4-carboxylic acids with different hydrazides in POCl3. All the synthesized compounds (4a-n) were characterized by IR, NMR, mass spectra and elemental analyses. Synthesized 1,3,4-oxadiazole derivatives were screened for their antibacterial activity against three different strains, namely Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa, while antifungal activity was determined against three different strains Aspergillus flavus, Chrysosporium keratinophilum and Candida albicans. The investigation of antimicrobial screening revealed that compounds 4i and 4j exhibited excellent activity when compared with the standard drugs. © 2013 King Saud University.
  • No Thumbnail Available
    Item
    Degradation of Triclosan from Domestic Wastewater by Biosurfactant Produced from Bacillus licheniformis
    (Humana Press Inc. humana@humanapr.com, 2019) Jayalatha, N.A.; Devatha, C.P.
    The use of triclosan (TCS), an antimicrobial agent in consumer product, results in adverse effects on the environment due to its wide usage all over the world. The present study focused on TCS detection and attempted for degradation by biosurfactant produced by Bacillus licheniformis from domestic wastewater in Surathkal region, Karnataka, India. The experimental investigation includes biosurfactant production using crude sunflower oil and detection and degradation of TCS from wastewater by High-Performance Liquid Chromatography (HPLC). Results exhibited that maximum biosurfactant yield (7.8 g/L) was achieved using 1 g/L of glycerol as carbon and 5.5 g/L of ammonium bicarbonate as a nitrogen source. Detection of TCS from domestic wastewater (0.36 mg/L) and degradation was carried out by HPLC. The result discloses that 47.2% and 100% removal of TCS was achieved in 2 h and 16 h for 1:1(v/v) ratio of wastewater and biosurfactant. © 2019, Springer Science+Business Media, LLC, part of Springer Nature.