Faculty Publications
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Item Efficient biosorption of Pb(II) on Pteris vittata L. from aqueous solution using pulsed plate column technique(Bellwether Publishing, Ltd. customerservice@taylorandfrancis.com, 2020) Prabhu, S.; Srinikethan, S.; Hegde, S.Biosorption is an alternative method of remediation that is devoid of the limitations associated with physiochemical techniques. This paper investigates the ability of the pteridophyte, Pteris vittata L., proven to have heavy metal hyper-accumulation capacity in living forms, to adsorb Pb(II) from an aqueous system in its powdered and pelletized form. At best-operating conditions, P. vittata L. pinnae powder exhibited Pb(II) biosorption capacity of 125 mg/g. Bench-scale Pulsed Plate column studies using pelletized biosorbent demonstrated continuous Pb(II) removal efficiency of 99.93%. With no commercial value and application, untreated P. vittata is a potential resource that will contribute to biosorption technology. © 2019 Taylor & Francis Group, LLC.Item Tailoring solulan C24 based niosomes for transdermal delivery of donepezil: In vitro characterization, evaluation of pH sensitivity, and microneedle-assisted Ex vivo permeation studies(Editions de Sante editions.de.sante@wanadoo.fr, 2020) Nayak, A.S.; Chodisetti, S.; Gadag, S.; Nayak, U.Y.; Srinikethan, S.; Raval, K.The present investigation aims at encapsulating donepezil (DNP) in a niosomes to avert the side effects and to deliver the intact carrier across the skin barrier by modulating its physicochemical properties. The finding conclusively demonstrated that entrapment efficiency and the alteration in the niosome size are associated with the change in the span 60: cholesterol ratio, sonication, and hydration volume. The addition of 5 mM of solulan C24 to the optimized formulation (NSV5SolC24) formed stable niosomes with a mean particle size of 180.1 ± 1.83 nm and entrapment efficiency of 82.15% ± 1.54%. The cryo-SEM image and in vitro drug release profile revealed that the NSV5SolC24 is pH-sensitive. FTIR spectral analysis of NSV5SolC24 suggested that the ether and ester group in the NSV5SolC24 complex undergoes SN2 cleavage and hydrolysis at lower pH, thus enhancing DNP release. The microneedle (MN)-assisted studies with MN1200 showed a 29-fold increase in transdermal permeation of intact NSV5SolC24 against the passive method in porcine skin. The intact NSV5SolC24 carrying DNP was translocated across the skin barrier successfully at a steady flux rate of 9.89 ± 0.923 ?g/cm2/h. Nevertheless, further in vivo studies are recommended to elucidate the pH sensitivity and clinical efficacy of the prepared drug delivery system. © 2020 Elsevier B.V.Item 'RS' and 'GIS' based air quality atlas with integrated land use and land cover change analysis in India(ICE Publishing, 2021) Navalgund, N.; Joshi, K.; Srinikethan, S.; Shet, V.B.; Hosamane, S.N.In this paper, the effect of land use and land cover and the impact of urbanisation on respirable particulate matter (RSPM), sulfur oxide (SO x ) and nitrogen oxide (NO x ) of the Hubli-Dharwad, a Tier II city in India, are correlated based on the trends in air quality observed from 2006 to 2013, population from 1990 to 2010, the number of vehicles between the periods of 2004 and 2013 and urbanisation between the periods of 1975 and 2009. It has been found that urbanisation has increased threefold from 92 km2 in 1975 to 271 km2 in 2009 and the corresponding decrease in agricultural area was from 368.22 to 123.43 km2. The RSPM in the study region is increasing at a rate of 8.9% per year. The study shows that vehicular pollutants are the major cause of air pollution, followed by industries, with the highest RSPM value of 128 ?g/m3 at traffic junctions in the Hubli-Dharwad region in 2013. Based on the trend analysis, the air quality atlas predicted for 2030 shows that the RSPM level in the air will reach 150 ?g/m3, well above the national ambient air quality standards, and will have serious consequences on human health if proper strategies are not undertaken. Owing to the unique geographical setting of Hubli-Dharwad, its future urbanisation will be in a narrow area, which may lead to a severe air pollution problem that needs immediate attention to provide a safe environment. © 2021 ICE Publishing: All rights reserved.Item Chemical characterization and source apportionment of ambient PM10 in Hubli-Dharwad region, Karnataka, India(World Research Association, 2021) Navalgund, N.; Keshava, J.; Krishna, K.; Srinikethan, S.; Sampagaon, N.; Manoj, K.; Aishwaraya, S.In India, particulate matter (PM10) shows very strong persistence and very high levels in most of the tier-II cities along with metropolitan cities and other cities of the world. The present work was to study air pollution (PM10) in Hubli-Dharwad, a tier-II city of Karnataka, India. The mean mass concentration for PM10 varied from 260-410 ppm, substantially higher than guidelines of CPCB. Seasonal variations of these pollutants indicated that higher concentrations of pollutants were observed in summer than in winter seasons with air quality index (AQI) as 211 in summer. The source apportionment study using positive matrix factorization (PMF5) indicated the presence of heavy metals in the atmosphere. Out of 4 identified factors, motor vehicles contributed vastly (38.8%), dust (16.4%), industrial emission (19.8%) and biomass burning (25.0%). This study has found that the source apportionment has distinct regional and seasonal characteristics. Such studies are essential for the Government to make region specific control strategies for particulate pollution in India. © 2021 World Research Association. All rights reserved.