Faculty Publications
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Item A nonlocal deep image prior model to restore optical coherence tomographic images from gamma distributed speckle noise(Taylor and Francis Ltd., 2021) Smitha, A.; Padikkal, P.Optical Coherence Tomography (OCT) is often employed to observe the retinal layers in the human eyes. The retinal scans are susceptible to artefacts such as head movements or eye blinks. Along with this, the quality of the images is degraded by speckle noise caused due to the constructive and destructive interference of the waves used for capturing data. Recently, image restoration techniques have geared up in terms of quality with the exertion of deep learning. Despeckling using deep learning, in general, necessitates a large set of training images. On the contrary, deep image prior is a novel model that performs denoising operations using a single training image, based on a prior assumption about the noise distribution. This paper extends the concept of the deep image prior towards non-local restoration for speckle noise assuming that the speckle follows Gamma distribution. Such a framework can be incorporated to enhance the OCT images. The proposed framework is assessed qualitatively with visual comparisons and quantitatively using statistical measures like PSNR, CNR and ENL. Comparative studies confirm that the proposed method outperforms the existing methods in restoring speckled input images. © 2021 Informa UK Limited, trading as Taylor & Francis Group.Item A retinex based non-local total generalized variation framework for OCT image restoration(Elsevier Ltd, 2022) Smitha, A.; Febin, I.P.; Padikkal, P.A retinex driven non-local total generalized variational (TGV) model is proposed in this paper to restore and enhance speckled images. The combined first and second-order TGV controlled by a balancing parameter are used to improve the enhancement and restoration process. The distribution of the speckle is estimated from input images using detailed statistical analysis. The model is designed to handle speckle-noise following a Gamma distribution, as analyzed later in this paper. The non-local TGV model is shown to restore images without causing any visual artefacts, unlike the normal total variation (TV) model. Moreover, a retinex framework shows a remarkable improvement to the contrast features of the data without distorting the natural image characteristics as quantified visually and statistically in the experimental section of this work. A fast numerical approximation based on the Split-Bregman scheme is employed to improve the efficiency of the model in terms of computation. The proposed model is verified to have despeckled and enhanced the Optical Coherence Tomography (OCT) data to a greater extent compared to the state-of-the-art models as observable from the results shown in this paper. © 2021 Elsevier LtdItem Detection of retinal disorders from OCT images using generative adversarial networks(Springer, 2022) Smitha, A.; Padikkal, J.Retinal image analysis has opened up a new window for prompt diagnosis and detection of various retinal disorders. Optical Coherence Tomography (OCT) is one of the major diagnostic tools to identify retinal abnormalities related to macular disorders like Age-Related Macular Degeneration (AMD) and Diabetic Macular Edema (DME). The clinical findings include retinal layer analysis to spot the abnormalities on OCT images. Though various models are proposed over the years to diagnose these disorders automatically, an end-to-end system that performs automatic denoising, segmentation, and classification does not exist to the best of our knowledge. This paper proposes a Generative Adversarial Network (GAN) based approach for automated segmentation and classification of OCT-B scans to diagnose AMD and DME. The proposed method incorporates the integration of handcrafted Gabor features to enhance the retina layer segmentation and non-local denoising to remove speckle noise. The classification metrics of GAN are compared with existing methods. The accuracy of up to 92.42% and F1-score of 0.79 indicates that the GANs can perform well for segmentation and classification of OCT images. © 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.