Faculty Publications

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Author: search.filters.author.Saxena, P.U.P.

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    Multi-Modal Medical Image Fusion with Adaptive Weighted Combination of NSST Bands Using Chaotic Grey Wolf Optimization
    (Institute of Electrical and Electronics Engineers Inc., 2019) Asha, C.S.; Lal, S.; Gurupur, V.P.; Saxena, P.U.P.
    Recently, medical image fusion has emerged as an impressive technique in merging the medical images of different modalities. Certainly, the fused image assists the physician in disease diagnosis for effective treatment planning. The fusion process combines multi-modal images to incur a single image with excellent quality, retaining the information of original images. This paper proposes a multi-modal medical image fusion through a weighted blending of high-frequency subbands of nonsubsampled shearlet transform (NSST) domain via chaotic grey wolf optimization algorithm. As an initial step, the NSST is applied on source images to decompose into the multi-scale and multi-directional components. The low-frequency bands are fused based on a simple max rule to sustain the energy of an individual. The texture details of input images are preserved by an adaptively weighted combination of high-frequency images using a recent chaotic grey wolf optimization algorithm to minimize the distance between the fused image and source images. The entire process emphasizes on retaining the energy of the low-frequency band and the transferring of texture features from source images to the fused image. Finally, the fused image is formed using inverse NSST of merged low and high-frequency bands. The experiments are carried out on eight different disease datasets obtained from Brain Atlas, which consists of MR-T1 and MR-T2, MR and SPECT, MR and PET, and MR and CT. The effectiveness of the proposed method is validated using more than 100 pairs of images based on the subjective and objective quality assessment. The experimental results confirm that the proposed method performs better in contrast with the current state-of-the-art image fusion techniques in terms of entropy, VIFF, and FMI. Hence, the proposed method will be helpful for disease diagnosis, medical treatment planning, and surgical procedure. © 2013 IEEE.
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    Classification and grade prediction of kidney cancer histological images using deep learning
    (Springer, 2024) Chanchal, A.K.; N, S.; Lal, S.; Kumar, S.; Saxena, P.U.P.
    Renal Cell Carcinoma (RCC) is the most common malignant tumor (85%) of kidney cancer and has a complex histological pattern and nuclear structure. The manual diagnosis of kidney cancer or any other cancer from histopathology image depends on the knowledge and experience of pathologists, and the pathologist’s experience influences the results. According to studies, the kind of histology in kidney cancer is related to the prognosis and course of treatment. Since the kind of histology, molecular profile, and stage of the disease all affect how the disease is treated, there is an essential need to develop an automated system that can precisely analyze the histopathological images of the disease. This work demonstrates how a deep learning framework can be used to predict and classify associated grades of RCC from provided haematoxylin and eosin (H &E) images. The proposed model focuses on two important tasks- First to capture and extract associated features from the H &E images of five different grades. Second, to classify the new set of unseen H &E images into five separate grades using the obtained features. The proposed architecture has been tested and experimented on two independent datasets containing H &E stained histopathology images. The proposed architecture has been examined using the following performance metrics namely precision, recall, F1 - score, accuracy, Floating-point operations (FLOPs), and the total number of parameters. The obtained results show that the proposed architecture attains better results over seven state-of-the-art deep learning architectures on two different H &E stained histopathology image datasets. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024.