Faculty Publications

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Publications by NITK Faculty

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Author: search.filters.author.S. Krishnan, G.S.Subject: search.filters.subject.Healthcare analytics

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    A supervised learning approach for ICU mortality prediction based on unstructured electrocardiogram text reports
    (Springer Verlag service@springer.de, 2018) S. Krishnan, G.S.; Kamath S․, S.
    Extracting patient data documented in text-based clinical records into a structured form is a predominantly manual process, both time and cost-intensive. Moreover, structured patient records often fail to effectively capture the nuances of patient-specific observations noted in doctors’ unstructured clinical notes and diagnostic reports. Automated techniques that utilize such unstructured text reports for modeling useful clinical information for supporting predictive analytics applications can thus be highly beneficial. In this paper, we propose a neural network based method for predicting mortality risk of ICU patients using unstructured Electrocardiogram (ECG) text reports. Word2Vec word embedding models were adopted for vectorizing and modeling textual features extracted from the patients’ reports. An unsupervised data cleansing technique for identification and removal of anomalous data/special cases was designed for optimizing the patient data representation. Further, a neural network model based on Extreme Learning Machine architecture was proposed for mortality prediction. ECG text reports available in the MIMIC-III dataset were used for experimental validation. The proposed model when benchmarked against four standard ICU severity scoring methods, outperformed all by 10–13%, in terms of prediction accuracy. © 2018, Springer International Publishing AG, part of Springer Nature.
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    A Supervised Approach for Patient-Specific ICU Mortality Prediction Using Feature Modeling
    (Springer Verlag service@springer.de, 2019) S. Krishnan, G.S.; Kamath S․, S.K.
    Intensive Care Units (ICUs) are one of the most essential, but expensive healthcare services provided in hospitals. Modern monitoring machines in critical care units continuously generate huge amount of data, which can be used for intelligent decision-making. Prediction of mortality risk of patients is one such predictive analytics application, which can assist hospitals and healthcare personnel in making informed decisions. Traditional scoring systems currently in use are parametric scoring methods which often suffer from low accuracy. In this paper, an empirical study on the effect of feature selection on the feature set of traditional scoring methods for modeling an optimal feature set to represent each patient’s profile along with a supervised learning approach for ICU mortality prediction have been presented. Experimental evaluation of the proposed approach in comparison to standard severity scores like SAPS-II, SOFA and OASIS showed that the proposed model outperformed them by a margin of 12–16% in terms of prediction accuracy. © 2019, Springer Nature Singapore Pte Ltd.
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    TAGS: Towards Automated Classification of Unstructured Clinical Nursing Notes
    (Springer Verlag service@springer.de, 2019) Gangavarapu, T.; Jayasimha, A.; S. Krishnan, G.S.; Kamath S․, S.K.
    Accurate risk management and disease prediction are vital in intensive care units to channel prompt care to patients in critical conditions and aid medical personnel in effective decision making. Clinical nursing notes document subjective assessments and crucial information of a patient’s state, which is mostly lost when transcribed into Electronic Medical Records (EMRs). The Clinical Decision Support Systems (CDSSs) in the existing body of literature are heavily dependent on the structured nature of EMRs. Moreover, works which aim at benchmarking deep learning models are limited. In this paper, we aim at leveraging the underutilized treasure-trove of patient-specific information present in the unstructured clinical nursing notes towards the development of CDSSs. We present a fuzzy token-based similarity approach to aggregate voluminous clinical documentations of a patient. To structure the free-text in the unstructured notes, vector space and coherence-based topic modeling approaches that capture the syntactic and latent semantic information are presented. Furthermore, we utilize the predictive capabilities of deep neural architectures for disease prediction as ICD-9 code group. Experimental validation revealed that the proposed Term weighting of nursing notes AGgregated using Similarity (TAGS) model outperformed the state-of-the-art model by 5% in AUPRC and 1.55% in AUROC. © 2019, Springer Nature Switzerland AG.