Faculty Publications

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    Magnetic resonance image denoising using nonlocal maximum likelihood paradigm in DCT-framework
    (John Wiley and Sons Inc, 2015) Kumar, P.K.; Darshan, P.; Kumar, S.; Ravindra, R.; Rajan, J.; Saba, L.; Suri, J.S.
    The data acquired by magnetic resonance (MR) imaging system are inherently degraded by noise that has its origin in the thermal Brownian motion of electrons. Denoising can enhance the quality (by improving the SNR) of the acquired MR image, which is important for both visual analysis and other post processing operations. Recent works on maximum likelihood (ML) based denoising shows that ML methods are very effective in denoising MR images and has an edge over the other state-of-the-art methods for MRI denoising. Among the ML based approaches, the Nonlocal maximum likelihood (NLML) method is commonly used. In the conventional NLML method, the samples for the ML estimation of the unknown true pixel are chosen in a nonlocal fashion based on the intensity similarity of the pixel neighborhoods. Euclidean distance is generally used to measure this similarity. It has been recently shown that computing similarity measure is more robust in discrete cosine transform (DCT) subspace, compared with Euclidean image subspace. Motivated by this observation, we integrated DCT into NLML to produce an improved MRI filtration process. Other than improving the SNR, the time complexity of the conventional NLML can also be significantly reduced through the proposed approach. On synthetic MR brain image, an average improvement of 5% in PSNR and 86%reduction in execution time is achieved with a search window size of 91 × 91 after incorporating the improvements in the existing NLML method. On an experimental kiwi fruit image an improvement of 10% in PSNR is achieved. We did experiments on both simulated and real data sets to validate and to demonstrate the effectiveness of the proposed method. © 2015 Wiley Periodicals, Inc. Int J Imaging Syst Technol, 25, 256-264, 2015 © 2015 Wiley Periodicals, Inc.
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    Segmentation of intima media complex from carotid ultrasound images using wind driven optimization technique
    (Elsevier Ltd, 2018) Yamanakkanavar, Y.; Madipalli, P.; Rajan, J.; Kumar, P.K.; Narasimhadhan, A.V.
    Cardiovascular diseases are the third leading cause of death worldwide. The primitive indication of the possible onset of a cardiovascular disease is atherosclerosis, which is the accumulation of plaque on the arterial wall. The intima-media thickness (IMT) of the common carotid artery is an early marker of the development of cardiovascular disease. The computation of the IMT and the delineation of the carotid plaque are significant predictors for the clinical diagnosis of the risk of stroke. For a robust diagnosis, carotid ultrasound images must be free from speckle noise. To address this problem, we use state-of-the-art despeckling and enhancement methods in this work. Many edge-based methods for IMT estimation have been proposed to overcome the limitations of manual segmentation. In this paper, we present a fully automated region-of-interest (ROI) extraction and a threshold-based segmentation of the intima media complex (IMC) using a wind driven optimization (WDO) technique. A quantitative evaluation is carried out on 90 carotid ultrasound images of two different datasets. The obtained results are compared with those of state-of-the-art techniques such as a model-based approach, a dynamic programming method, and a snake segmentation method. The experimental analysis shows that the proposed method is robust in measuring the IMT in carotid ultrasound images. © 2017 Elsevier Ltd
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    Stack generalized deep ensemble learning for retinal layer segmentation in Optical Coherence Tomography images
    (Elsevier Sp. z o.o., 2020) Anoop, B.N.; Pavan, R.; Girish, G.N.; Kothari, A.R.; Rajan, J.
    Segmentation of retinal layers is a vital and important step in computerized processing and the study of retinal Optical Coherence Tomography (OCT) images. However, automatic segmentation of retinal layers is challenging due to the presence of noise, widely varying reflectivity of image components, variations in morphology and alignment of layers in the presence of retinal diseases. In this paper, we propose a Fully Convolutional Network (FCN) termed as DelNet based on a deep ensemble learning approach to selectively segment retinal layers from OCT scans. The proposed model is tested on a publicly available DUKE DME dataset. Comparative analysis with other state-of-the-art methods on a benchmark dataset shows that the performance of DelNet is superior to other methods. © 2020 Nalecz Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences