Faculty Publications
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Publications by NITK Faculty
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Item Iterative bilateral filter for Rician noise reduction in MR images(Springer London, 2015) Riji, R.; Rajan, J.; Sijbers, J.; Nair, M.S.Noise removal from magnetic resonance images is important for further processing and visual analysis. Bilateral filter is known for its effectiveness in edge-preserved image denoising. In this paper, an iterative bilateral filter for filtering the Rician noise in the magnitude magnetic resonance images is proposed. The proposed iterative bilateral filter improves the denoising efficiency, preserves the fine structures and also reduces the bias due to Rician noise. The visual and diagnostic quality of the image is well preserved. The quantitative analysis based on the standard metrics like peak signal-to-noise ratio and mean structural similarity index matrix shows that the proposed method performs better than the other recently proposed denoising methods for MRI. © 2014, Springer-Verlag London.Item A nonlocal maximum likelihood estimation method for enhancing magnetic resonance phase maps(Springer London, 2017) Sudeep, P.V.; Ponnusamy, P.; Kesavadas, C.; Sijbers, J.; den Dekker, A.J.; Rajan, J.A phase map can be obtained from the real and imaginary components of a complex valued magnetic resonance (MR) image. Many applications, such as MR phase velocity mapping and susceptibility mapping, make use of the information contained in the MR phase maps. Unfortunately, noise in the complex MR signal affects the measurement of parameters related to phase (e.g, the phase velocity). In this paper, we propose a nonlocal maximum likelihood (NLML) estimation method for enhancing phase maps. The proposed method estimates the true underlying phase map from a noisy MR phase map. Experiments on both simulated and real data sets indicate that the proposed NLML method has a better performance in terms of qualitative and quantitative evaluations when compared to state-of-the-art methods. © 2016, Springer-Verlag London.Item An improved nonlocal maximum likelihood estimation method for denoising magnetic resonance images with spatially varying noise levels(Elsevier B.V., 2020) Sudeep, P.V.; Ponnusamy, P.; Kesavadas, C.; Rajan, J.Magnetic resonance images (MRI) reconstructed with parallel MRI (pMRI) techniques generally have spatially varying (non-stationary) noise levels. However, most of the existing MRI denoising methods rely on a stationary noise model and end with suboptimal results when applied to pMRI images. To address this problem, this paper proposes an improved nonlocal maximum likelihood (NLML) estimation method. In the proposed method, a noise map is computed with a robust noise estimator before the ML estimation of the underlying signal. Also, a similarity measure based on local frequency descriptors (LFD) is introduced to find the nonlocal samples for ML estimation. The experiments on simulated and real magnetic resonance (MR) data demonstrate that the proposed technique has superior filtering capabilities in terms of subjective and quantitative assessments when compared with other state-of-the-art methods. © 2018 Elsevier B.V.Item Segmentation of focal cortical dysplasia lesions from magnetic resonance images using 3D convolutional neural networks(Elsevier Ltd, 2021) Niyas, S.; Chethana Vaisali, S.; Show, I.; Chandrika, T.G.; Vinayagamani, S.; Kesavadas, C.; Rajan, J.Computer-aided diagnosis using advanced Artific ial Intelligence (AI) techniques has become much popular over the last few years. This work automates the segmentation of Focal Cortical Dysplasia (FCD) lesions from three-dimensional (3D) Magnetic Resonance (MR) images. FCD is a type of neuronal malformation in the brain cortex and is the leading cause of intractable epilepsy, irrespective of gender or age differences. Since the neuron related abnormalities are usually resistant to drug therapy, surgical resection has been the main treatment approach for patients with intractable epilepsy. Automating the identification and segmentation of FCD is useful for neuroradiologists in pre-surgical evaluations. Convolutional Neural Networks (CNNs) have the ability to learn appropriate features from the training data without any human intervention. But, most of the state-of-the-art FCD segmentation approaches use two-dimensional (2D) CNN models despite the availability of 3D Magnetic resonance imaging (MRI) volumes, and hence fail to leverage the inter-slice information present in the MRI volumes. The major hurdles in considering a 3D CNN model are the need for a large 3D dataset, big memory, and high computation cost. A deep 3D CNN segmentation model, which can extract inter-slice information and overcomes the drawbacks of conventional 3D CNN methods to an extent, is proposed in this paper. The model uses a 3D version of U-Net with residual blocks that works on shallow depth 3D sub-volumes generated from MRI volumes. The proposed method shows superior performance over the state-of-the-art FCD segmentation methods in both qualitative and quantitative analysis. © 2021 Elsevier Ltd
