Faculty Publications
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Item A Lightweight Convolutional Neural Network Model for Tuberculosis Bacilli Detection From Microscopic Sputum Smear Images(wiley, 2021) Panicker, R.O.; Pawan, S.J.; Rajan, J.; Sabu, M.K.This chapter describes a lightweight convolutional neural network model that automatically detects Tuberculosis (TB) bacilli from sputum smear microscopic images. According to WHO, about onefourth of the population in the universe is infected with TB, and every day five thousand people are killed due to TB disease. There are well-known recommended diagnostics are available for TB detection, among them sputum smear microscopic examination is a primary and most efficient recommended method for most of the developing and moderately developed countries. However, this manual detection method is highly error-prone and time-consuming. In this chapter, we proposed a lightweight CNN model for classifying Tuberculosis bacilli from non-bacilli objects. We adopted a Convolutional Neural Network (CNN) architecture with a skip connection of variable lengths that can identify TB bacilli from sputum smear microscopic images. The performance of the proposed model in terms of accuracy is close to the state-of-the-art. However, the number of parameters in the proposed model is significantly less than other recently proposed models. © 2021 Scrivener Publishing LLC.Item Multi-Res-Attention UNet: A CNN Model for the Segmentation of Focal Cortical Dysplasia Lesions from Magnetic Resonance Images(Institute of Electrical and Electronics Engineers Inc., 2021) Thomas, E.; Pawan, S.J.; Kumar, S.; Horo, A.; Niyas, S.; Vinayagamani, S.; Kesavadas, C.; Rajan, J.In this work, we have focused on the segmentation of Focal Cortical Dysplasia (FCD) regions from MRI images. FCD is a congenital malformation of brain development that is considered as the most common causative of intractable epilepsy in adults and children. To our knowledge, the latest work concerning the automatic segmentation of FCD was proposed using a fully convolutional neural network (FCN) model based on UNet. While there is no doubt that the model outperformed conventional image processing techniques by a considerable margin, it suffers from several pitfalls. First, it does not account for the large semantic gap of feature maps passed from the encoder to the decoder layer through the long skip connections. Second, it fails to leverage the salient features that represent complex FCD lesions and suppress most of the irrelevant features in the input sample. We propose Multi-Res-Attention UNet; a novel hybrid skip connection-based FCN architecture that addresses these drawbacks. Moreover, we have trained it from scratch for the detection of FCD from 3 T MRI 3D FLAIR images and conducted 5-fold cross-validation to evaluate the model. FCD detection rate (Recall) of 92% was achieved for patient wise analysis. © 2013 IEEE.Item Capsule Network–based architectures for the segmentation of sub-retinal serous fluid in optical coherence tomography images of central serous chorioretinopathy(Springer Science and Business Media Deutschland GmbH, 2021) Pawan, S.J.; Sankar, R.; Jain, A.; Jain, M.; Darshan, D.V.; Anoop, B.N.; Kothari, A.R.; Venkatesan, M.; Rajan, J.Central serous chorioretinopathy (CSCR) is a chorioretinal disorder of the eye characterized by serous detachment of the neurosensory retina at the posterior pole of the eye. CSCR results from the accumulation of subretinal fluid (SRF) due to idiopathic defects at the level of the retinal pigment epithelial (RPE) that allows serous fluid from the choriocapillaris to diffuse into the subretinal space between RPE and neurosensory retinal layers. This condition is presently investigated by clinicians using invasive angiography or non-invasive optical coherence tomography (OCT) imaging. OCT images provide a representation of the fluid underlying the retina, and in the absence of automated segmentation tools, currently only a qualitative assessment of the same is used to follow the progression of the disease. Automated segmentation of the SRF can prove to be extremely useful for the assessment of progression and for the timely management of CSCR. In this paper, we adopt an existing architecture called SegCaps, which is based on the recently introduced Capsule Networks concept, for the segmentation of SRF from CSCR OCT images. Furthermore, we propose an enhancement to SegCaps, which we have termed as DRIP-Caps, that utilizes the concepts of Dilation, Residual Connections, Inception Blocks, and Capsule Pooling to address the defined problem. The proposed model outperforms the benchmark UNet architecture while reducing the number of trainable parameters by 54.21%. Moreover, it reduces the computation complexity of SegCaps by reducing the number of trainable parameters by 37.85%, with competitive performance. The experiments demonstrate the generalizability of the proposed model, as evidenced by its remarkable performance even with a limited number of training samples. [Figure not available: see fulltext.]. © 2021, International Federation for Medical and Biological Engineering.Item Semi-supervised structure attentive temporal mixup coherence for medical image segmentation(Elsevier B.V., 2022) Pawan, S.J.; Jeevan, G.; Rajan, J.Deep convolutional neural networks have shown eminent performance in medical image segmentation in supervised learning. However, this success is predicated on the availability of large volumes of pixel-level labeled data, making these approaches impractical when labeled data is scarce. On the other hand, semi-supervised learning utilizes pertinent information from unlabeled data along with minimal labeled data, alleviating the demand for labeled data. In this paper, we leverage the mixup-based risk minimization operator in a student–teacher-based semi-supervised paradigm along with structure-aware constraints to enforce consistency coherence among the student predictions for unlabeled samples and the teacher predictions for the corresponding mixup sample by significantly diminishing the need for labeled data. Besides, due to the intrinsic simplicity of the linear combination operation used for generating mixup samples, the proposed method stands at a computational advantage over existing consistency regularization-based SSL methods. We experimentally validate the performance of the proposed model on two public benchmark datasets, namely the Left Atrial (LA) and Automatic Cardiac Diagnosis Challenge (ACDC) datasets. Notably, on the LA dataset's lowest labeled data set-up (5%), the proposed method significantly improved the Dice Similarity Coefficient and the Jaccard Similarity Coefficient by 1.08% and 1.46%, respectively. Furthermore, we demonstrate the efficacy of the proposed method with a consistent improvement across various labeled data proportions on the aforementioned datasets. © 2022 Nalecz Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences