Faculty Publications
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Item NucleiSegNet: Robust deep learning architecture for the nuclei segmentation of liver cancer histopathology images(Elsevier Ltd, 2021) Lal, S.; Das, D.; Alabhya, K.; Kanfade, A.; Kumar, A.; Kini, J.R.The nuclei segmentation of hematoxylin and eosin (H&E) stained histopathology images is an important prerequisite in designing a computer-aided diagnostics (CAD) system for cancer diagnosis and prognosis. Automated nuclei segmentation methods enable the qualitative and quantitative analysis of tens of thousands of nuclei within H&E stained histopathology images. However, a major challenge during nuclei segmentation is the segmentation of variable sized, touching nuclei. To address this challenge, we present NucleiSegNet - a robust deep learning network architecture for the nuclei segmentation of H&E stained liver cancer histopathology images. Our proposed architecture includes three blocks: a robust residual block, a bottleneck block, and an attention decoder block. The robust residual block is a newly proposed block for the efficient extraction of high-level semantic maps. The attention decoder block uses a new attention mechanism for efficient object localization, and it improves the proposed architecture's performance by reducing false positives. When applied to nuclei segmentation tasks, the proposed deep-learning architecture yielded superior results compared to state-of-the-art nuclei segmentation methods. We applied our proposed deep learning architecture for nuclei segmentation to a set of H&E stained histopathology images from two datasets, and our comprehensive results show that our proposed architecture outperforms state-of-the-art methods. As part of this work, we also introduced a new liver dataset (KMC liver dataset) of H&E stained liver cancer histopathology image tiles, containing 80 images with annotated nuclei procured from Kasturba Medical College (KMC), Mangalore, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India. The proposed model's source code is available at https://github.com/shyamfec/NucleiSegNet. © 2020 Elsevier LtdItem Deep structured residual encoder-decoder network with a novel loss function for nuclei segmentation of kidney and breast histopathology images(Springer, 2022) Chanchal, A.K.; Lal, S.; Kini, J.To improve the process of diagnosis and treatment of cancer disease, automatic segmentation of haematoxylin and eosin (H & E) stained cell nuclei from histopathology images is the first step in digital pathology. The proposed deep structured residual encoder-decoder network (DSREDN) focuses on two aspects: first, it effectively utilized residual connections throughout the network and provides a wide and deep encoder-decoder path, which results to capture relevant context and more localized features. Second, vanished boundary of detected nuclei is addressed by proposing an efficient loss function that better train our proposed model and reduces the false prediction which is undesirable especially in healthcare applications. The proposed architecture experimented on three different publicly available H&E stained histopathological datasets namely: (I) Kidney (RCC) (II) Triple Negative Breast Cancer (TNBC) (III) MoNuSeg-2018. We have considered F1-score, Aggregated Jaccard Index (AJI), the total number of parameters, and FLOPs (Floating point operations), which are mostly preferred performance measure metrics for comparison of nuclei segmentation. The evaluated score of nuclei segmentation indicated that the proposed architecture achieved a considerable margin over five state-of-the-art deep learning models on three different histopathology datasets. Visual segmentation results show that the proposed DSREDN model accurately segment the nuclear regions than those of the state-of-the-art methods. © 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.Item O-SegNet: Robust Encoder and Decoder Architecture for Objects Segmentation from Aerial Imagery Data(Institute of Electrical and Electronics Engineers Inc., 2022) Eerapu, K.K.; Lal, S.; Narasimhadhan, A.V.The segmentation of diversified roads and buildings from high-resolution aerial images is essential for various applications, such as urban planning, disaster assessment, traffic congestion management, and up-to-date road maps. However, a major challenge during object segmentation is the segmentation of small-sized, diverse shaped roads, and buildings in dominant background scenarios. We introduce O-SegNet- the robust encoder and decoder architecture for objects segmentation from high-resolution aerial imagery data to address this challenge. The proposed O-SegNet architecture contains Guided-Attention (GA) blocks in the encoder and decoder to focus on salient features by representing the spatial dependencies between features of different scales. Further, GA blocks guide the successive stages of encoder and decoder by interrelating the pixels of the same class. To emphasize more on relevant context, the attention mechanism is provided between encoder and decoder after aggregating the global context via an 8 Level Pyramid Pooling Network (PPN). The qualitative and quantitative results of the proposed and existing semantic segmentation architectures are evaluated by utilizing the dataset provided by Kaiser et al. Further, we show that the proposed O-SegNet architecture outperforms state-of-the-art techniques by accurately preserving the road connectivity and structure of buildings. © 2017 IEEE.Item A Robust CNN Framework for Change Detection Analysis From Bitemporal Remote Sensing Images(Institute of Electrical and Electronics Engineers Inc., 2024) Sravya, N.; Bhaduka, K.; Lal, S.; Nalini, J.; Chintala, C.S.—Deep learning (DL) algorithms are currently the most effective methods for change detection (CD) from high-resolution multispectral (MS) remote-sensing (RS) images. Because a variety of satellites are able to provide a lot of data, it is now easy to find changes using efficient DL models. Current CD methods focus on simple structure and combining the features obtained by all the stages together rather than extracting multiscale features from a single stage since it may lead to information loss and an imbalance contribution of features at different stages. This in turn results in misclassification of small changed areas and poor edge and shape preservation of changed areas. This article introduces an enhanced RSCD network (ERSCDNet) for CD from bitemporal aerial and MS images. The proposed encoder–decoder-based ERSCDNet model uses an attention-based encoder and decoder block and a modified new spatial pyramid pooling block at each stage of the decoder part, which effectively utilize features at each encoder stages and prevent information loss. The learning, vision, and remote sensing CD (LEVIR-CD), Onera satellite change detection (OSCD), and Sun Yat-Sen University CD (SYSU-CD) datasets are used to evaluate the ERSCDNet model. The ERSCDNet gives better performance than all the models used in this article for comparison. It gives an F1 score, a Kappa coefficient, and a Jaccard index of (0.9306, 0.9282, 0.8703), (0.8945, 0.8887, 0.8091), and (0.7581, 0.6876, 0.6103) on OSCD, LEVIR-CD, and SYSU-CD datasets, respectively. © 2024 The Authors. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.