Faculty Publications
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Item A semi-automatic method for carotid artery wall segmentation in MR images(Institute of Electrical and Electronics Engineers Inc., 2017) Kumar, P.K.; Kesavadas, C.; Rajan, J.The quantification of carotid artery stenosis via imaging techniques guides the physicians to take a decision regarding surgical interventions. The measurement of wall thickness from magnetic resonance (MR) images is a promising approach to measure the degree of carotid stenosis. Manual tracing of the carotid vessel walls is time consuming and is sensitive to observer variability. Further, the existing segmentation techniques are limited by the poor contrast and presence of noise in MR images. The objective this paper is to present a novel segmentation strategy for carotid lumen and outer wall from MR images. The segmentation has been carried out in two stages which starts with a user assisted region of interest selection. In the first stage, an active contour based global segmentation has been applied to classify the lumen region. In the second stage, morphological gradient of the region of interest has been computed. This is followed by particle swarm optimization based localized segmentation to separate the wall region. The results demonstrate excellent correspondence between the automatic and manual tracings for lumen and outer walls of the carotid artery. © 2016 IEEE.Item Lattice Heating Effects on Electric Field and Potential for a Silicon on Insulator (SOI) MOSFET for MIMO Applications(Institute of Electrical and Electronics Engineers Inc., 2023) Kumar, P.K.; Srikanth, K.; Boddukuri, N.K.; Suresh, N.; Vani, B.V.Finding substitutes for Silicon dioxide materials is necessary when technology is scaled back. TheSOI device conceals the self heating effects induced in the MOSFET. There exists an active path of conduction from the drain to substrate and source to substrate in the entire device to curb the heating effects. The buried oxide layer used in the device is SiO2 and it is essentially free from the issues related to fabrication and performance. The comparison is made from the bulk MOSFET and SOI MOSFET from the literature. The Silicon (Si) and Silicon Germanium (SiGe) materials are considered for the analysis. The lattice temperature effects are induced for the comparative analysis of the proposed SOI MOSFET. The main parameters of interest in the study are the electric field (lateral and vertical) and potential across the channel. © 2023 IEEE.Item A Review on Carotid Ultrasound Atherosclerotic Tissue Characterization and Stroke Risk Stratification in Machine Learning Framework(Current Medicine Group LLC 1 info@phl.cursci.com, 2015) Sharma, A.M.; Gupta, A.; Kumar, P.K.; Rajan, J.; Saba, L.; Nobutaka, I.; Laird, J.R.; Nicolades, A.; Suri, J.S.Cardiovascular diseases (including stroke and heart attack) are identified as the leading cause of death in today’s world. However, very little is understood about the arterial mechanics of plaque buildup, arterial fibrous cap rupture, and the role of abnormalities of the vasa vasorum. Recently, ultrasonic echogenicity characteristics and morphological characterization of carotid plaque types have been shown to have clinical utility in classification of stroke risks. Furthermore, this characterization supports aggressive and intensive medical therapy as well as procedures, including endarterectomy and stenting. This is the first state-of-the-art review to provide a comprehensive understanding of the field of ultrasonic vascular morphology tissue characterization. This paper presents fundamental and advanced ultrasonic tissue characterization and feature extraction methods for analyzing plaque. Additionally, the paper shows how the risk stratification is achieved using machine learning paradigms. More advanced methods need to be developed which can segment the carotid artery walls into multiple regions such as the bulb region and areas both proximal and distal to the bulb. Furthermore, multimodality imaging is needed for validation of such advanced methods for stroke and cardiovascular risk stratification. © 2015, Springer Science+Business Media New York.Item State-of-the-art review on automated lumen and adventitial border delineation and its measurements in carotid ultrasound(Elsevier Ireland Ltd, 2018) Kumar, P.K.; Araki, T.; Rajan, J.; Laird, J.R.; Nicolaïdes, A.; Suri, J.S.Background and objective: Accurate, reliable, efficient, and precise measurements of the lumen geometry of the common carotid artery (CCA) are important for (a) managing the progression/regression of atherosclerotic build-up and (b) the risk of stroke. The image-based degree of stenosis in the carotid artery and the plaque burden can be predicted using the automated carotid lumen diameter (LD)/inter-adventitial diameter (IAD) measurements from B-mode ultrasound images. The objective of this review is to present the state-of-the-art methods and systems for the measurement of LD/IAD in CCA based on automated or semi-automated strategies. Further, the performance of these systems is compared based on various metrics for its measurements. Methods: The automated algorithms proposed for the segmentation of carotid lumen are broadly classified into two different categories as: region-based and boundary-based. These techniques are discussed in detail specifying their pros and cons. Further, we discuss the challenges encountered in the segmentation process along with its quantitative assessment. Lastly, we present stenosis quantification and risk stratification strategies. Results: Even though, we have found more boundary-based approaches compared to region-based approaches in the literature, however, the region-based strategy yield more satisfactory performance. Novel risk stratification strategies are presented. On a patient database containing 203 patients, 9 patients are identified as high risk patients, whereas 27 patients are identified as medium risk patients. Conclusions: We have presented different techniques for the lumen segmentation of the common carotid artery from B-mode ultrasound images and measurement of lumen diameter and inter-adventitial diameter. We believe that the issue regarding boundary-based techniques can be compensated by taking regional statistics embedded with boundary-based information. © 2018 Elsevier B.V.Item Magnetic resonance image denoising using nonlocal maximum likelihood paradigm in DCT-framework(John Wiley and Sons Inc, 2015) Kumar, P.K.; Darshan, P.; Kumar, S.; Ravindra, R.; Rajan, J.; Saba, L.; Suri, J.S.The data acquired by magnetic resonance (MR) imaging system are inherently degraded by noise that has its origin in the thermal Brownian motion of electrons. Denoising can enhance the quality (by improving the SNR) of the acquired MR image, which is important for both visual analysis and other post processing operations. Recent works on maximum likelihood (ML) based denoising shows that ML methods are very effective in denoising MR images and has an edge over the other state-of-the-art methods for MRI denoising. Among the ML based approaches, the Nonlocal maximum likelihood (NLML) method is commonly used. In the conventional NLML method, the samples for the ML estimation of the unknown true pixel are chosen in a nonlocal fashion based on the intensity similarity of the pixel neighborhoods. Euclidean distance is generally used to measure this similarity. It has been recently shown that computing similarity measure is more robust in discrete cosine transform (DCT) subspace, compared with Euclidean image subspace. Motivated by this observation, we integrated DCT into NLML to produce an improved MRI filtration process. Other than improving the SNR, the time complexity of the conventional NLML can also be significantly reduced through the proposed approach. On synthetic MR brain image, an average improvement of 5% in PSNR and 86%reduction in execution time is achieved with a search window size of 91 × 91 after incorporating the improvements in the existing NLML method. On an experimental kiwi fruit image an improvement of 10% in PSNR is achieved. We did experiments on both simulated and real data sets to validate and to demonstrate the effectiveness of the proposed method. © 2015 Wiley Periodicals, Inc. Int J Imaging Syst Technol, 25, 256-264, 2015 © 2015 Wiley Periodicals, Inc.Item Two Automated Techniques for Carotid Lumen Diameter Measurement: Regional versus Boundary Approaches(Springer New York LLC barbara.b.bertram@gsk.com, 2016) Araki, T.; Kumar, P.K.; Suri, H.S.; Ikeda, N.; Gupta, A.; Saba, L.; Rajan, J.; Lavra, F.; Sharma, A.M.; Shafique, S.; Nicolaïdes, A.; Laird, J.R.; Suri, J.S.The degree of stenosis in the carotid artery can be predicted using automated carotid lumen diameter (LD) measured from B-mode ultrasound images. Systolic velocity-based methods for measurement of LD are subjective. With the advancement of high resolution imaging, image-based methods have started to emerge. However, they require robust image analysis for accurate LD measurement. This paper presents two different algorithms for automated segmentation of the lumen borders in carotid ultrasound images. Both algorithms are modeled as a two stage process. Stage one consists of a global-based model using scale-space framework for the extraction of the region of interest. This stage is common to both algorithms. Stage two is modeled using a local-based strategy that extracts the lumen interfaces. At this stage, the algorithm-1 is modeled as a region-based strategy using a classification framework, whereas the algorithm-2 is modeled as a boundary-based approach that uses the level set framework. Two sets of databases (DB), Japan DB (JDB) (202 patients, 404 images) and Hong Kong DB (HKDB) (50 patients, 300 images) were used in this study. Two trained neuroradiologists performed manual LD tracings. The mean automated LD measured was 6.35 ± 0.95 mm for JDB and 6.20 ± 1.35 mm for HKDB. The precision-of-merit was: 97.4 % and 98.0 % w.r.t to two manual tracings for JDB and 99.7 % and 97.9 % w.r.t to two manual tracings for HKDB. Statistical tests such as ANOVA, Chi-Squared, T-test, and Mann-Whitney test were conducted to show the stability and reliability of the automated techniques. © 2016, Springer Science+Business Media New York.Item Segmentation of intima media complex from carotid ultrasound images using wind driven optimization technique(Elsevier Ltd, 2018) Yamanakkanavar, Y.; Madipalli, P.; Rajan, J.; Kumar, P.K.; Narasimhadhan, A.V.Cardiovascular diseases are the third leading cause of death worldwide. The primitive indication of the possible onset of a cardiovascular disease is atherosclerosis, which is the accumulation of plaque on the arterial wall. The intima-media thickness (IMT) of the common carotid artery is an early marker of the development of cardiovascular disease. The computation of the IMT and the delineation of the carotid plaque are significant predictors for the clinical diagnosis of the risk of stroke. For a robust diagnosis, carotid ultrasound images must be free from speckle noise. To address this problem, we use state-of-the-art despeckling and enhancement methods in this work. Many edge-based methods for IMT estimation have been proposed to overcome the limitations of manual segmentation. In this paper, we present a fully automated region-of-interest (ROI) extraction and a threshold-based segmentation of the intima media complex (IMC) using a wind driven optimization (WDO) technique. A quantitative evaluation is carried out on 90 carotid ultrasound images of two different datasets. The obtained results are compared with those of state-of-the-art techniques such as a model-based approach, a dynamic programming method, and a snake segmentation method. The experimental analysis shows that the proposed method is robust in measuring the IMT in carotid ultrasound images. © 2017 Elsevier LtdItem High-Resolution Fiber Optic Sensor based on Coated Linearly Chirped Bragg Grating(Elsevier GmbH, 2020) Singh, M.; Raghuwanshi, S.K.; Prakash, O.; Kumar, P.K.a fiber optic strain sensor is proposed and experimentally demonstrated using fiber Bragg grating (FBG) based interrogation scheme. Due to fast response time and better sensitivity of graphene oxide (GO) material, coated linearly chirped fiber Bragg grating (LCFBG) is used in this work. Interrogation scheme is used for the efficient strain sensing by placing LCFBG within the Sagnac loop (wavelength dependent receiver). The GO deposition is confirmed by ultraviolet–visible spectroscopy, atomic force microscopy (AFM), and field emission scanning electron micrograph (FESEM). Our proposed fiber optic strain sensor possesses better resolution, stable operation in the infra-red region. In addition, sensor demonstrates 5.25 ?? static strain and 0.645 ??/?Hz dynamic strain resolutions, respectively. © 2020 Elsevier GmbHItem Supportive culture and job involvement in public sector: the mediating role of participation in decision making and organizational learning(Emerald Group Holdings Ltd., 2022) Kumar, P.K.; Saha, S.; Anand, A.Purpose: The purpose of this study is to determine whether participation in decision-making (PDM) and organizational learning (OL) act as mediating factors in the relationship between supportive culture and job involvement. Design/methodology/approach: Data were collected from 712 employees working in different public sector undertakings (PSUs) across India. Necessary condition analysis (NCA) analysis and partial least square (PLS) analysis were used to test the proposed hypotheses. Findings: The findings of the present study indicated that PDM and OL act as a full mediator respectively in the relationship between supportive culture (SC) and job involvement (JI). The SC was positively and significantly related to PDM and OL. However, SL did not have a significant impact on JI. In addition, higher PDM and OL were found to be significantly impacting JI. Practical implications: The results suggest that PDM and OL facilitate the impact of SC on JI and may help organizations to retain their employees. The implications of these findings for all hierarchical levels in PSUs are discussed. Originality/value: OL and PDM as mediators between SC and JI have received very little attention from the context of India. The results add to the growing literature of culture from a non-western context as this study is based on Indian samples. This study has taken care to provide unbiased responses by utilizing data from employees working in various functional units of the organizations. © 2022, Emerald Publishing Limited.
