Faculty Publications
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Item Ensemble deep neural models for automated abnormality detection and classification in precision care applications(Elsevier, 2023) Karthik, K.; Mayya, V.; Kamath S․, S.Radiological imaging is one of the most relied upon modalities in the clinical diagnosis and treatment planning process. Conventional diagnosis involves the manual analysis of radiology images by experienced radiologists, which is often a time-consuming and labor-intensive process. The scarcity of experienced radiologists and necessity of large-scale X-rays image analysis given the huge diagnosis workload at most hospitals stresses the need for automated clinical diagnosis systems capable of fast and accurate identification of abnormalities, disease characteristic identification, disease classification, and others. Such automated methods are thus a fundamental requirement in clinical workflow management applications. In this work, we present an approach for multitask clinical objectives such as disease classification and detection of abnormalities. The proposed model leverages the predictive power of deep neural models for enabling evidence-based diagnosis. During validation experiments, the model achieved an accuracy of 89.58% along with sensitivity and specificity of 85.83% and 90.83%, respectively, with an AUC (area under the ROC curve) of 95.84% for normal/no findings versus COVID-19 chest radiograph classification and an accuracy of 73.19% for upper extremity musculoskeletal images. The performance of the model for the classification and abnormality identification tasks, when benchmarked over multiple standard datasets, emphasizes its suitability and adaptability in real-world clinical settings, with significant improvements in radiology-based diagnosis workflow and patient care. © 2023 Elsevier Inc. All rights reserved.Item MSDNet: a deep neural ensemble model for abnormality detection and classification of plain radiographs(Springer Science and Business Media Deutschland GmbH, 2023) Karthik, K.; Kamath S․, S.S.Modern medical diagnostic techniques facilitate accurate diagnosis and treatment recommendations in healthcare. Such diagnostics procedures are performed daily in large numbers, thus, the clinical interpretation workload of radiologists is very high. Identification of abnormalities is a predominantly manual task that is performed by radiologists before the medical scans are available to the patient’s referring doctor for further recommendations. On the other hand, for a radiologist to delineate the imaging study’s findings/observations as a textual report is also a tedious task. Automated methods for radiographic image examination for identifying abnormalities and generating reliable radiology report are thus a fundamental requirement in clinical workflow management applications. In this work, we present an automated approach for abnormality classification, localization and diagnostic report retrieval for identified abnormalities. We propose MSDNet, an ensemble of Convolutional Neural models for abnormality classification, which combines the features of multiple CNN models to enhance abnormality classification performance. The proposed model also is designed to localize and visualize the detected abnormality on the radiograph image, based on an abnormal region detection algorithm to further optimize the diagnosis quality. Furthermore, the extracted features generated by MSDNet are used to automatically generate the diagnosis text report using an automatic content-based report retrieval algorithm. The upper extremity musculo-skeletal images from the MURA dataset and chest X-ray images from Indiana dataset were used for the experimental evaluation of the proposed approach. The proposed model achieved promising results, with an accuracy of 82.69%, showing its significant impact on alleviating radiologists’ cognitive load, thus improving the overall efficiency. © 2022, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
