Faculty Publications

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    Efficient fuzzy clustering based approach to brain tumor segmentation on MR images
    (2011) Arakeri, M.P.; Guddeti, G.
    Image segmentation is one of the most vital and significant step in medical applications. The conventional fuzzy c-means (FCM) clustering is the most widely used unsupervised clustering method for brain tumor segmentation on magnetic resonance (MR) images. However, the major limitation of the conventional FCM is its huge computational time and it is sensitive to initial cluster centers. In this paper, we present a novel efficient FCM algorithm to eliminate the drawback of conventional FCM. The proposed algorithm is formulated by incorporating distribution of the gray level information in the image and a new objective function which ensures better stability and compactness of clusters. Experiments are conducted on brain MR images to investigate the effectiveness of the proposed method in segmenting brain tumor. The conventional FCM and the proposed method are compared to explore the efficiency and accuracy of the proposed method. © 2011 Springer-Verlag.
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    An intelligent content-based image retrieval system for clinical decision support in brain tumor diagnosis
    (Springer London, 2013) Arakeri, M.P.; Guddeti, G.
    Accurate diagnosis is crucial for successful treatment of the brain tumor. Accordingly in this paper, we propose an intelligent content-based image retrieval (CBIR) system which retrieves similar pathology bearing magnetic resonance (MR) images of the brain from a medical database to assist the radiologist in the diagnosis of the brain tumor. A single feature vector will not perform well for finding similar images in the medical domain as images within the same disease class differ by severity, density and other such factors. To handle this problem, the proposed CBIR system uses a two-step approach to retrieve similar MR images. The first step classifies the query image as benign or malignant using the features that discriminate the classes. The second step then retrieves the most similar images within the predicted class using the features that distinguish the subclasses. In order to provide faster image retrieval, we propose an indexing method called clustering with principal component analysis (PCA) and KD-tree which groups subclass features into clusters using modified K-means clustering and separately reduces the dimensionality of each cluster using PCA. The reduced feature set is then indexed using a KD-tree. The proposed CBIR system is also made robust against misalignment that occurs during MR image acquisition. Experiments were carried out on a database consisting of 820 MR images of the brain tumor. The experimental results demonstrate the effectiveness of the proposed system and show the viability of clinical application. © 2013, Springer-Verlag London.