Faculty Publications

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    Predicting ICD-9 code groups with fuzzy similarity based supervised multi-label classification of unstructured clinical nursing notes
    (Elsevier B.V., 2020) Gangavarapu, T.; Jayasimha, A.; S. Krishnan, G.S.; Kamath S?, S.
    In hospitals, caregivers are trained to chronicle the subtle changes in the clinical conditions of a patient at regular intervals, for enabling decision-making. Caregivers’ text-based clinical notes are a significant source of rich patient-specific data, that can facilitate effective clinical decision support, despite which, this treasure-trove of data remains largely unexplored for supporting the prediction of clinical outcomes. The application of sophisticated data modeling and prediction algorithms with greater computational capacity have made disease prediction from raw clinical notes a relevant problem. In this paper, we propose an approach based on vector space and topic modeling, to structure the raw clinical data by capturing the semantic information in the nursing notes. Fuzzy similarity based data cleansing approach was used to merge anomalous and redundant patient data. Furthermore, we utilize eight supervised multi-label classification models to facilitate disease (ICD-9 code group) prediction. We present an exhaustive comparative study to evaluate the performance of the proposed approaches using standard evaluation metrics. Experimental validation on MIMIC-III, an open database, underscored the superior performance of the proposed Term weighting of unstructured notes AGgregated using fuzzy Similarity (TAGS) model, which consistently outperformed the state-of-the-art structured data based approach by 7.79% in AUPRC and 1.24% in AUROC. © 2019 Elsevier B.V.
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    FarSight: Long-Term Disease Prediction Using Unstructured Clinical Nursing Notes
    (IEEE Computer Society, 2021) Gangavarapu, T.; S. Krishnan, G.S.; Kamath S?, S.; Jeganathan, J.
    Accurate risk stratification using patient data is a vital task in channeling prioritized care. Most state-of-the-art models are predominantly reliant on digitized data in the form of structured Electronic Health Records (EHRs). Those models overlook the valuable patient-specific information embedded in unstructured clinical notes, which is the prevalent medium employed by caregivers to record patients' disease timeline. The availability of such patient-specific data presents an unprecedented opportunity to build intelligent systems that provide exclusive insights into patients' disease physiology. Moreover, very few works have attempted to benchmark the performance of deep neural architectures against the state-of-the-art models on publicly available datasets. This article presents significant observations from our benchmarking experiments on the applicability of deep learning models for the clinical task of ICD-9 code group prediction. We present FarSight, a long-term aggregation mechanism intended to recognize the onset of the disease with the earliest detected symptoms. Vector space and topic modeling approaches are utilized to capture the semantic information in the patient representations. Experiments on MIMIC-III database underscored the superior performance of the proposed models built on unstructured data when compared to structured EHR based state-of-the-art model, achieving an improvement of 19.34 percent in AUPRC and 5.41 percent in AUROC. © 2013 IEEE.