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Item Digital watermarking is a technique of hiding specific identification data for copyright authentication. This technique is adapted here for interleaving patient information with medical images to reduce storage and transmission overheads. The text data are encrypted before interleaving with images to ensure greater security. The graphical signals are compressed and subsequently interleaved with the image. Differential pulse-code-modulation and adaptive-delta-modulation techniques are employed for data compression, and encryption and results are tabulated for a specific example.(Compact storage of medical images with patient information) Acharya, A.U.; Anand, D.; P, S.B.; C, N.U.2001Item Background. Digital watermarking is a technique of hiding specific identification data for copyright authentication. This technique is adapted here for interleaving patient information with medical images, to reduce storage and transmission overheads. Methods. The patient information is encrypted before interleaving with images to ensure greater security. The bio-signals are compressed and subsequently interleaved with the image. This interleaving is carried out in the spatial domain and Frequency domain. The performance of interleaving in the spatial, Discrete Fourier Transform (DFT), Discrete Cosine Transform (DCT) and Discrete Wavelet Transform (DWT) coefficients is studied. Differential pulse code modulation (DPCM) is employed for data compression as well as encryption and results are tabulated for a specific example. Results. It can be seen from results, the process does not affect the picture quality. This is attributed to the fact that the change in LSB of a pixel changes its brightness by 1 part in 256. Spatial and DFT domain interleaving gave very less %NRMSE as compared to DCT and DWT domain. Conclusion. The Results show that spatial domain the interleaving, the %NRMSE was less than 0.25% for 8-bit encoded pixel intensity. Among the frequency domain interleaving methods, DFT was found to be very efficient. © 2004 Nayak et al, licensee BioMed Central Ltd.(Simultaneous storage of medical images in the spatial and frequency domain: A comparative study) Nayak, J.; Subbanna Bhat, P.; Acharya, A.U.; Niranjan, U.C.2004