Journal Articles
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Item Speckle reduction in medical ultrasound images using an unbiased non-local means method(Elsevier Ltd, 2016) Sudeep, P.V.; Ponnusamy, P.; Rajan, J.; Baradaran, H.; Saba, L.; Gupta, A.; Suri, J.S.Enhancement of ultrasound (US) images is required for proper visual inspection and further pre-processing since US images are generally corrupted with speckle. In this paper, a new approach based on non-local means (NLM) method is proposed to remove the speckle noise in the US images. Since the interpolated final Cartesian image produced from uncompressed ultrasound data contaminated with fully developed speckle can be represented by a Gamma distribution, a Gamma model is incorporated in the proposed denoising procedure. In addition, the scale and shape parameters of the Gamma distribution are estimated using the maximum likelihood (ML) method. Bias due to speckle noise is expressed using these parameters and is removed from the NLM filtered output. The experiments on phantom images and real 2D ultrasound datasets show that the proposed method outperforms other related well-accepted methods, both in terms of objective and subjective evaluations. The results demonstrate that the proposed method has a better performance in both speckle reduction and preservation of structural features. © 2016 Elsevier Ltd. All rights reserved.Item GPU implementation of non-local maximum likelihood estimation method for denoising magnetic resonance images(Springer Verlag service@springer.de, 2017) Upadhya, A.H.K.; Talawar, B.; Rajan, J.Magnetic resonance imaging (MRI) is a widely deployed medical imaging technique used for various applications such as neuroimaging, cardiovascular imaging and musculoskeletal imaging. However, MR images degrade in quality due to noise. The magnitude MRI data in the presence of noise generally follows a Rician distribution if acquired with single-coil systems. Several methods are proposed in the literature for denoising MR images corrupted with Rician noise. Amongst the methods proposed in literature for denoising MR images corrupted with Rician noise, the non-local maximum likelihood methods (NLML) and its variants are popular. In spite of the performance and denoising quality, NLML algorithm suffers from a tremendous time complexity O(m3N3) , where m3 and N3 represent the search window and image size, respectively, for a 3D image. This makes the algorithm challenging for deployment in the real-time applications where fast and prompt results are required. A viable solution to this shortcoming would be the application of a data parallel processing framework such as Nvidia CUDA so as to utilize the mutually exclusive and computationally intensive calculations to our advantage. The GPU-based implementation of NLML-based image denoising achieves significant speedup compared to the serial implementation. This research paper describes the first successful attempt to implement a GPU-accelerated version of the NLML algorithm. The main focus of the research was on the parallelization and acceleration of one computationally intensive section of the algorithm so as to demonstrate the execution time improvement through the application of parallel processing concepts on a GPU. Our results suggest the possibility of practical deployment of NLML and its variants for MRI denoising. © 2016, Springer-Verlag Berlin Heidelberg.Item Perceptually lossless coder for volumetric medical image data(Academic Press Inc. apjcs@harcourt.com, 2017) Chandrika, B.K.; Aparna., P.; Sumam David, S.S.With the development of modern imaging techniques, every medical examination would result in a huge volume of image data. Analysis, storage and/or transmission of these data demands high compression without any loss of diagnostically significant data. Although, various 3-D compression techniques have been proposed, they have not been able to meet the current requirements. This paper proposes a novel method to compress 3-D medical images based on human vision model to remove visually insignificant information. The block matching algorithm applied to exploit the anatomical symmetry remove the spatial redundancies. The results obtained are compared with those of lossless compression techniques. The results show better compression without any degradation in visual quality. The rate-distortion performance of the proposed coders is compared with that of the state-of-the-art lossy coders. The subjective evaluation performed by the medical experts confirms that the visual quality of the reconstructed image is excellent. © 2017Item Gradient-oriented directional predictor for HEVC planar and angular intra prediction modes to enhance lossless compression(Elsevier GmbH journals@elsevier.com, 2018) Shilpa Kamath, S.; Aparna., P.; Antony, A.Recent advancements in the capture and display technologies motivated the ITU-T Video Coding Experts Group and ISO/IEC Moving Picture Experts Group to jointly develop the High-Efficiency Video Coding (HEVC), a state-of-the-art video coding standard for efficient compression. The compression applications that essentially require lossless compression scenarios include medical imaging, video analytics, video surveillance, video streaming etc., where the content reconstruction should be flawless. In the proposed work, we present a gradient-oriented directional prediction (GDP) strategy at the pixel level to enhance the compression efficiency of the conventional block-based planar and angular intra prediction in the HEVC lossless mode. The detailed experimental analysis demonstrates that the proposed method outperforms the lossless mode of HEVC anchor in terms of bit-rate savings by 8.29%, 1.65%, 1.94% and 2.21% for Main-AI, LD, LDP and RA configurations respectively, without impairing the computational complexity. The experimental results also illustrates that the proposed predictor performs superior to the existing state-of-the-art techniques in the literature. © 2018 Elsevier GmbHItem Noise classification and automatic restoration system using non-local regularization frameworks(Taylor and Francis Ltd. michael.wagreich@univie.ac.at, 2018) Febin, I.P.; Padikkal, P.; Bini, A.A.Medical, satellite or microscopic images differ in the imaging techniques used, hence their underlying noise distribution also are different. Most of the restoration methods including regularization models make prior assumptions about the noise to perform an efficient restoration. Here we propose a system that estimates and classifies the noise into different distributions by extracting the relevant features. The system provides information about the noise distribution and then it gets directed into the restoration module where an appropriate regularization method (based on the non-local framework) has been employed to provide an efficient restoration of the data. We have effectively addressed the distortion due to data-dependent noise distributions such as Poisson and Gamma along with data uncorrelated Gaussian noise. The studies have shown a 97.7% accuracy in classifying noise in the test data. Moreover, the system also shows the capability to cater to other popular noise distributions such as Rayleigh, Chi, etc. © 2018, © 2018 The Royal Photographic Society.Item Multi-Modal Medical Image Fusion with Adaptive Weighted Combination of NSST Bands Using Chaotic Grey Wolf Optimization(Institute of Electrical and Electronics Engineers Inc., 2019) Asha, C.S.; Lal, S.; Gurupur, V.P.; Saxena, P.U.P.Recently, medical image fusion has emerged as an impressive technique in merging the medical images of different modalities. Certainly, the fused image assists the physician in disease diagnosis for effective treatment planning. The fusion process combines multi-modal images to incur a single image with excellent quality, retaining the information of original images. This paper proposes a multi-modal medical image fusion through a weighted blending of high-frequency subbands of nonsubsampled shearlet transform (NSST) domain via chaotic grey wolf optimization algorithm. As an initial step, the NSST is applied on source images to decompose into the multi-scale and multi-directional components. The low-frequency bands are fused based on a simple max rule to sustain the energy of an individual. The texture details of input images are preserved by an adaptively weighted combination of high-frequency images using a recent chaotic grey wolf optimization algorithm to minimize the distance between the fused image and source images. The entire process emphasizes on retaining the energy of the low-frequency band and the transferring of texture features from source images to the fused image. Finally, the fused image is formed using inverse NSST of merged low and high-frequency bands. The experiments are carried out on eight different disease datasets obtained from Brain Atlas, which consists of MR-T1 and MR-T2, MR and SPECT, MR and PET, and MR and CT. The effectiveness of the proposed method is validated using more than 100 pairs of images based on the subjective and objective quality assessment. The experimental results confirm that the proposed method performs better in contrast with the current state-of-the-art image fusion techniques in terms of entropy, VIFF, and FMI. Hence, the proposed method will be helpful for disease diagnosis, medical treatment planning, and surgical procedure. © 2013 IEEE.Item An Efficient Technique for Three-Dimensional Image Visualization through Two-Dimensional Images for Medical Data(De Gruyter peter.golla@degruyter.com, 2020) Gunasekaran, G.; Venkatesan, M.The main idea behind this work is to present three-dimensional (3D) image visualization through two-dimensional (2D) images that comprise various images. 3D image visualization is one of the essential methods for excerpting data from given pieces. The main goal of this work is to figure out the outlines of the given 3D geometric primitives in each part, and then integrate these outlines or frames to reconstruct 3D geometric primitives. The proposed technique is very useful and can be applied to many kinds of images. The experimental results showed a very good determination of the reconstructing process of 2D images. © 2020 Walter de Gruyter GmbH, Berlin/Boston 2020.Item Multiple-Coil Magnetic Resonance Image Denoising and Deblurring With Nonlocal Total Bounded Variation(Taylor and Francis Ltd. michael.wagreich@univie.ac.at, 2020) Holla Kayyar, K.S.; Padikkal, P.; Bini, A.A.One of the complex tasks in image restoration is to restore images under data correlated noise contaminations. In real-time medical imaging scenarios, such as Magnetic Resonance (MR), Ultrasound, Computed Tomography(CT) etc, it is observed that, the data of interest is severely degraded with data dependent noise interventions. A Nonlocal Total Bounded Variation (NLTBV) approach is being proposed in this paper to denoise as well as deblur multiple-coil MR images corrupted by non-central Chi distributed noise and linear Gaussian blur. The energy functional for the restoration model is derived by applying the Maximum A Posteriori (MAP) estimator on the Probability Density Function (PDF) of the non-central Chi distribution. The numerical implementation is performed using the split-Bregman iterative scheme to improve the convergence rate. The proposed model is compared with the other state of the art models in terms of both visual and statistical quantifications to demonstrate it's performance. © 2019, © 2019 IETE.Item Performance of ultra-wide band DCBLNA with suspended strip line radiator for human breast cancer diagnosis medical imaging application(Institution of Engineering and Technology, 2020) Roy, G.M.; Kumar Kanaujia, B.K.; Dwari, S.; Kumar, S.; Song, H.This study presents the performance of differential cascode balun low noise amplifier (DCBLNA) with ultra-wideband (UWB) for human breast cancer diagnosis. The proposed DCBLNA design-I with bulky spiral inductors achieves insufficient bandwidth with large power consumption of 10.8 mW. To attain the proper UWB band of operation, suspended strip line (SSLIN) radiators have employed in the proposed design-I. The performance of SSLIN is evaluated in terms of line capacitance and characteristic impedance by optimising its width. It is observed that best 50 ?n-II. DCBLNA design-II using SSLIN have achieving a desired band of operation ranging from 1.5 to 15.7 GHz and best NF of 0.5 dB. The gain and phase imperfections are simulated to characterise balun networks. The smallest gain imperfection achieved is 0.1 dB at 10 GHz while the simulated phase imperfection turns out to be sufficiently good with 2.35° at 8 GHz. The proposed DCBLNA design-II is implemented and fabricated using RFCMOS 45 nm Taiwan Semiconductor Manufacturing Company (TSMC) process under commercial conditions. The highest figure of merit comes out to be 3.2 that ensures good accuracy of medical imaging for breast cancer diagnosis. © The Institution of Engineering and Technology 2020.Item FarSight: Long-Term Disease Prediction Using Unstructured Clinical Nursing Notes(IEEE Computer Society, 2021) Gangavarapu, T.; S. Krishnan, G.S.; Kamath S?, S.; Jeganathan, J.Accurate risk stratification using patient data is a vital task in channeling prioritized care. Most state-of-the-art models are predominantly reliant on digitized data in the form of structured Electronic Health Records (EHRs). Those models overlook the valuable patient-specific information embedded in unstructured clinical notes, which is the prevalent medium employed by caregivers to record patients' disease timeline. The availability of such patient-specific data presents an unprecedented opportunity to build intelligent systems that provide exclusive insights into patients' disease physiology. Moreover, very few works have attempted to benchmark the performance of deep neural architectures against the state-of-the-art models on publicly available datasets. This article presents significant observations from our benchmarking experiments on the applicability of deep learning models for the clinical task of ICD-9 code group prediction. We present FarSight, a long-term aggregation mechanism intended to recognize the onset of the disease with the earliest detected symptoms. Vector space and topic modeling approaches are utilized to capture the semantic information in the patient representations. Experiments on MIMIC-III database underscored the superior performance of the proposed models built on unstructured data when compared to structured EHR based state-of-the-art model, achieving an improvement of 19.34 percent in AUPRC and 5.41 percent in AUROC. © 2013 IEEE.