Browsing by Author "Sogra Fathima, B."

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    Biosynthesis and optimization of silver nanoparticles by endophytic fungus Fusarium solani
    (Elsevier, 2014) Sogra Fathima, B.; Mohan Balakrishnan, R.M.
    A mathematical model for optimization of factors influencing the biosynthesis of silver nanoparticles by an endophytic fungus Fusarium solani was designed. A high determination coefficient R2 of 99.3% was obtained. Structural characterization by UV-vis, TEM, XRD and FTIR revealed the formation of spherical nanoparticles. © 2014 Elsevier B.V.
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    Total phenolics from an endophytic fungus Penicillium sp isolated from Nothapodytes foetida and its optimization
    (2014) Sogra Fathima, B.; Raj Mohan, B.
    Microwave Assisted Extraction (MAE) of total phenolic content (TPC) from an endophytic fungus Penicillium sp. was carried out and the conditions for extraction was optimized by Response Surface Methodology (RSM). The effects of operating conditions (extraction time, extraction temperature and ratio of solvent to sample) on the extraction of TPC were studied using Central Composite Design (CCD). TPC was determined by Folin's Ciocalteau method and the results were expressed in (mg GAE/g Biomass). The optimal processing parameters were found to have significant effect on the extraction of TPC from Penicillium sp. A mathematical model with high determination coefficient R2 of 0.947 was obtained with optimal conditions of extraction of 5.88 minutes, 51.87 °C, and ratio of solvent to sample of 18.66:1. Under these conditions the experimental yield of TPC was 59.42 mg GAE/g Biomass which was close to the predicted value of 59.88mg GAE/g Biomass. This study indicated the potential use of MAE for extraction of antioxidants from the biomass of an endophytic fungus.