Browsing by Author "Sinha, P."

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Bioinspired ZnS: Gd nanoparticles synthesized from an endophytic fungi Aspergillus flavus for fluorescence-based metal detection
(MDPI AG, 2019) Uddandarao, P.; Mohan Balakrishnan, R.M.; Ashok, A.; Swarup, S.; Sinha, P.
Recently, several nonconventional sources have emerged as strong hotspots for the biosynthesis of chalcogenide quantum dots. However, studies that have ascertained the biomimetic methodologies that initiate biosynthesis are rather limited. The present investigation portrays a few perspectives of rare-earth(Gd)-doped ZnS biosynthesis using the endophytic fungi Aspergillus flavus for sensing metals based on their fluorescence. Analysis of ZnS:Gd nanoparticles was performed by elemental analysis, energy-dispersive X-ray spectroscopy (EDS), atomic force microscopy (AFM), X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), photoluminescence (PL), and transmission electron microscopy (TEM). The results of TEM demonstrated that the particles were polycrystalline in nature, with a mean size of 10-18 nm. The fluorescence amenability of the biogenic ZnS nanoparticles was further used for the development of a simple and efficient sensing array. The results showed sensitive and detectable quenching/enhancement in the fluorescence of biogenic colloidal ZnS nanoparticles, in the presence of Pb (II), Cd (II), Hg (II), Cu (II) and Ni (II), respectively. The fluorescence intensity of the biogenic ZnS:Gd nanoparticles was found to increase compared to that of the ZnS nanoparticles that capacitate these systems as a reliable fluorescence sensing platform with selective environmental applications. © 2019 by the authors.
Evolution of LiverNet 2.x: Architectures for automated liver cancer grade classification from H&E stained liver histopathological images
(Springer, 2024) Chanchal, A.K.; Lal, S.; Barnwal, D.; Sinha, P.; Arvavasu, S.; Kini, J.
Recently, the automation of disease identification has been quite popular in the field of medical diagnosis. The rise of Convolutional Neural Networks (CNNs) for training and generalizing medical image data has proven to be quite efficient in detecting and identifying the types and sub-types of various diseases. Since the classification of large datasets of Hematoxylin & Eosin (H&E) stained histopathology images by experts can be expensive and time-consuming, automated processes using deep learning have been encouraged for the past decade. This paper introduces LiverNet 2.x model by modifying the previously encountered LiverNet architecture. The proposed model uses two different improvements of the Atrous Spatial Pyramid Pooling (ASPP) block to extract the clinically defined features of hepatocellular carcinoma (HCC) from liver histopathology images. LiverNet 2.0 uses a modified form of ASPP block known as DenseASPP, where all the atrous convolution outputs are densely connected. Whereas LiverNet 2.1 uses fewer concatenations while maintaining a large receptive field by stacking the dilated convolutional blocks in a tree-like fashion. This paper also discusses the trade-off between LiverNet 2.0 and LiverNet 2.1 in terms of accuracy and computational complexity. All comparison model and the proposed model is trained and tested on the patches of two different histopathological datasets. The experimental results show that the proposed model performs better compared to reference models. For the KMC Liver dataset, LiverNet 2.0 and LiverNet 2.1 achieved an accuracy of 97.50% and 97.14% respectively. Accuracy of 94.37% and 97.14% for the TCGA Liver dataset are achieved. © 2023, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
Investigating the "wisdom of crowds" at scale
(2015) Mysore, A.S.; Yaligar, V.S.; Ibarra, I.A.; Simoiu, C.; Goel, S.; Arvind, R.; Sumanth, C.; Srikantan, A.; Bhargav, H.S.; Pahadia, M.; Dobhal, T.; Ahmed, A.; Shankar, M.; Agarwal, H.; Agarwal, R.; Anirudh-Kondaveeti, S.; Arun-Gokhale, S.; Attri, A.; Chandra, A.; Chilukuri, Y.; Dharmaji, S.; Garg, D.; Gupta, N.; Gupta, P.; Jacob, G.M.; Jain, S.; Joshi, S.; Khajuria, T.; Khillan, S.; Konam, S.; Kumar-Kolla, P.; Loomba, S.; Madan, R.; Maharaja, A.; Mathur, V.; Munshi, B.; Nawazish, M.; Neehar-Kurukunda, V.; Nirmal-Gavarraju, V.; Parashar, S.; Parikh, H.; Paritala, A.; Patil, A.; Phatak, R.; Pradhan, M.; Ravichander, A.; Sangeeth, K.; Sankaranarayanan, S.; Sehgal, V.; Sheshan, A.; Shibiraj, S.; Singh, A.; Singh, A.; Sinha, P.; Soni, P.; Thomas, B.; Tuteja, L.; Varma-Dattada, K.; Venkataraman, S.; Verma, P.; Yelurwar, I.
In a variety of problem domains, it has been observed that the aggregate opinions of groups are often more accurate than those of the constituent individuals, a phenomenon that has been termed the "wisdom of the crowd." Yet, perhaps surprisingly, there is still little consensus on how generally the phenomenon holds, how best to aggregate crowd judgements, and how social influence affects estimates. We investigate these questions by taking a meta wisdom of crowds approach. With a distributed team of over 100 student researchers across 17 institutions in the United States and India, we develop a large-scale online experiment to systematically study the wisdom of crowds effect for 1,000 different tasks in 50 subject domains. These tasks involve various types of knowledge (e.g., explicit knowledge, tacit knowledge, and prediction), question formats (e.g., multiple choice and point estimation), and inputs (e.g., text, audio, and video). To examine the effect of social influence, participants are randomly assigned to one of three different experiment conditions in which they see varying degrees of information on the responses of others. In this ongoing project, we are now preparing to recruit participants via Amazon's Mechanical Turk.
Investigating the "wisdom of crowds" at scale
(Association for Computing Machinery, Inc acmhelp@acm.org, 2015) Mysore, A.S.; Yaligar, V.S.; Ibarra, I.A.; Simoiu, C.; Goel, S.; Arvind, R.; Sumanth, C.; Srikantan, A.; Bhargav, H.S.; Pahadia, M.; Dobhal, T.; Ahmed, A.; Shankar, M.; Agarwal, H.; Agarwal, R.; Anirudh-Kondaveeti, S.; Arun-Gokhale, S.; Attri, A.; Chandra, A.; Chilukuri, Y.; Dharmaji, S.; Garg, D.; Gupta, N.; Gupta, P.; Jacob, G.M.; Jain, S.; Joshi, S.; Khajuria, T.; Khillan, S.; Konam, S.; Kumar-Kolla, P.; Loomba, S.; Madan, R.; Maharaja, A.; Mathur, V.; Munshi, B.; Nawazish, M.; Neehar-Kurukunda, V.; Nirmal-Gavarraju, V.; Parashar, S.; Parikh, H.; Paritala, A.; Patil, A.; Phatak, R.; Pradhan, M.; Ravichander, A.; Sangeeth, K.; Sankaranarayanan, S.; Sehgal, V.; Sheshan, A.; Shibiraj, S.; Singh, A.; Singh, A.; Sinha, P.; Soni, P.; Thomas, B.; Tuteja, L.; Varma-Dattada, K.; Venkataraman, S.; Verma, P.; Yelurwar, I.
In a variety of problem domains, it has been observed that the aggregate opinions of groups are often more accurate than those of the constituent individuals, a phenomenon that has been termed the "wisdom of the crowd." Yet, perhaps surprisingly, there is still little consensus on how generally the phenomenon holds, how best to aggregate crowd judgements, and how social influence affects estimates. We investigate these questions by taking a meta wisdom of crowds approach. With a distributed team of over 100 student researchers across 17 institutions in the United States and India, we develop a large-scale online experiment to systematically study the wisdom of crowds effect for 1,000 different tasks in 50 subject domains. These tasks involve various types of knowledge (e.g., explicit knowledge, tacit knowledge, and prediction), question formats (e.g., multiple choice and point estimation), and inputs (e.g., text, audio, and video). To examine the effect of social influence, participants are randomly assigned to one of three different experiment conditions in which they see varying degrees of information on the responses of others. In this ongoing project, we are now preparing to recruit participants via Amazon's Mechanical Turk.