Browsing by Author "Sahu, J.K."

Filter results by typing the first few letters
Now showing 1 - 2 of 2
  • No Thumbnail Available
    Item
    Growth Reaction of Gold Nanorods in the Presence of Mutated Peptides and Amine-Modified Single-Stranded Nucleic Acids
    (John Wiley and Sons Ltd, 2023) Sahu, J.K.; Singh, O.; Chakraborty, D.; Sadhu, K.K.
    Conformation of biomolecules like DNA, peptides and amino acids play vital role during nanoparticle growth. Herein, we have experimentally explored the effect of different noncovalent interaction between a 5′-amine modified DNA sequence (NH2−C6H12-5′-ACATCAGT-3′, PMR) and arginine during the seed-mediated growth reaction of gold nanorods (GNRs). Amino acid-mediated growth reaction of GNRs results in a snowflake-like gold nanoarchitecture. However, in case of Arg, prior incubation of GNRs with PMR selectively produces sea urchin-like gold suprastructures, via strong hydrogen bonding and cation-π interaction between PMR and Arg. This distinctive structure formation strategy has been extended to study the structural modulation caused by two structurally close α-helical RRR (Ac-(AAAAR)3A−NH2) peptide and the lysine mutated KKR (Ac−AAAAKAAAAKAAAARA−NH2) peptide with partial helix at the amino terminus. Simulation studies confirm that a greater number of hydrogen bonding and cation-π interaction between the Arg residues and PMR resulted in the gold sea urchin structure for RRR peptide against KKR peptide. © 2023 Wiley-VCH GmbH.
  • No Thumbnail Available
    Item
    Optimisation of process parameters for dimensional stability in FDM
    (SAGE Publications Ltd, 2023) Sahu, J.K.; Sahu, R.K.; Katiyar, J.K.; Kiran, P.S.
    The fused deposition modelling (FDM) technique has been adopted in the present work to fabricate Acrylonitrile Butadiene Styrene (ABS) plastic components using input variables like layer thickness, orientation, infill rate and the number of shells. The dimensional geometrical changes of FDM printed built parts, that is, length, width and thickness variation, are optimised individually. Still, a confounding effect is found in the optimisation of individual responses. To overcome this issue, this study uses a fuzzy inference system as an artificially intelligent system. A fuzzy inference system transformed all the responses into one response, known as a multi-response performance index (MPI), and optimised the MPI coupled with Taguchi philosophy. The optimal parameter combination of FDM-printed ABS components for the slightest variation in length, width, and thickness was found to be layer thickness: 200 µm, orientation: 0°, infill rate: 20%,and the number of shells: 3. The significant parametric effect on the responses of FDM components was studied using analysis of variance, and the results reveal that orientation is the most influential parameter trailed by infill rate and the number of shells. © IMechE 2023.