Browsing by Author "Pandith, A."

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Corrosion inhibition of 2024-T3 aluminum alloy in 3.5% NaCl by thiosemicarbazone derivatives
(Elsevier Ltd, 2018) Prakashaiah, B.G.; Vinaya Kumara, D.; Pandith, A.; Nityananda Shetty, A.; Amitha Rani, B.E.
Three thiosemicarzone derivatives, namely (E)-2-(2-hydroxybenzylidene) hydrazinecarbothioamide(MHC), (E)-2-(2,4-dihydroxybenzylidene)hydrazinecarbothioamide (DHC) and (E)-2-(2,3,4-trihydroxybenzylidene)hydrazinecarbothioamide (THC) were synthesized and their corrosion inhibition action on 2024-T3 aluminum alloy was studied in 3.5% NaCl solution. The surface morphology and surface composition of the corroded alloy were examined using FESEM, 3D profilometry, EDX spectroscopy and X-ray photoelectron spectroscopy. The synthesized inhibitors were found to provide corrosion protection on AA2024-T3 by forming an adsorbed layer of the complex on the alloy surface. They exhibited inhibition efficiency in the order, MHC < DHC < THC. Quantum chemical calculations corroborated the experimental results. © 2018 Elsevier Ltd
Hydrogen bond-driven columnar self-assembly of electroluminescent D-A-D configured cyanopyridones
(2018) Vinayakumara, D.R.; Ulla, H.; Kumar, S.; Pandith, A.; Satyanarayan, M.N.; Rao, D.S.S.; Prasad, S.K.; Adhikari, A.V.
Herein, we report the design and synthesis of a new series of flying bird-shaped liquid crystalline (LC) cyanopyridone derivatives with a D-A-D architecture, CPO-1 to CPO-4. Their mesomorphic, photophysical, electrochemical, and electroluminescence characteristics have been investigated in detail. Here, the H-bonding interactions through a central lactam core were shown to be the key driving force for their self-assembly into columnar mesophases. The key role of H-bonding has been confirmed by using newly synthesized similar shaped compounds, MCP-1 to MCP-3. New CPO mesogens were found to be intense greenish blue light emitters with narrow band-gap energies. Conclusions were drawn based on theoretical studies also. Finally, the application potential of the selected mesogen CPO-2 as an emissive material has been demonstrated for the fabrication of doped and non-doped OLED devices with different device architectures, which displayed encouraging results. In fact, this is the first report on the use of emissive H-bond-assisted columnar liquid crystals in devices. The present results provide a new guideline and a versatile approach to the design of new LC molecules for the fabrication of efficient OLEDs. 2018 The Royal Society of Chemistry.
Hydrogen bond-driven columnar self-assembly of electroluminescent D-A-D configured cyanopyridones
(Royal Society of Chemistry, 2018) Vinayakumara, D.R.; Ulla, H.; Kumar, S.; Pandith, A.; Satyanarayan, M.N.; Shankar Rao, D.S.S.; Prasad, S.K.; Vasudeva Adhikari, A.
Herein, we report the design and synthesis of a new series of flying bird-shaped liquid crystalline (LC) cyanopyridone derivatives with a D-A-D architecture, CPO-1 to CPO-4. Their mesomorphic, photophysical, electrochemical, and electroluminescence characteristics have been investigated in detail. Here, the H-bonding interactions through a central lactam core were shown to be the key driving force for their self-assembly into columnar mesophases. The key role of H-bonding has been confirmed by using newly synthesized similar shaped compounds, MCP-1 to MCP-3. New CPO mesogens were found to be intense greenish blue light emitters with narrow band-gap energies. Conclusions were drawn based on theoretical studies also. Finally, the application potential of the selected mesogen CPO-2 as an emissive material has been demonstrated for the fabrication of doped and non-doped OLED devices with different device architectures, which displayed encouraging results. In fact, this is the first report on the use of emissive H-bond-assisted columnar liquid crystals in devices. The present results provide a new guideline and a versatile approach to the design of new LC molecules for the fabrication of efficient OLEDs. © 2018 The Royal Society of Chemistry.
Recent Advancements in Developments of Novel Fluorescent Probes: In Cellulo Recognitions of Alkaline Phosphatases
(MDPI, 2022) Dasnur Nanjappa, M.; Pandith, A.; Sankaran, S.; Dorairaj, D.P.; Reddy, A.A.; Ramesh, H.P.B.
Alkaline phosphatase (ALP) is one of the vital phospho-ester bond cleaving biocatalysts that has inevitable significance in cellular systems, viz., early-stage osteoblast differentiation, cell integrity in tissues, bone mineralization, cancer biomarker, liver dysfunction, cellular osmotic pressure, protein folding and many more. Variation from optimal levels of ALP in intra and extracellular fluids can cause severe diseases, including death. Due to these reasons, ALP is considered as a vital biomarker for various preclinical and medical diagnosis. Fluorescence image-based diagnosis is the most widely used method, owing to its simplicity, robustness, non-invasive properties and excellent spatio-temporal resolution (up to the nM/pM level), as compared to conventional analytical techniques, such as the electroanalytical method, nuclear magnetic resonance (NMR) and high-performance liquid chromatography (HPLC). Most of the reviews reported for ALPâ€™s recognition in the literature scarcely explain the structurally related, photophysical and biophysical parameters; and the sub-cellular localizations. Considering these facts, in order to enhance the opto-analytical parameters of fluorescence-based diagnostic materials at the cellular level, herein we have systematically documented recent developments in the opto-analytical capabilities of quencher-free probes for ALP, used in in vitro (biological buffers) to in cellulo conditions, along with in vivo models. Â© 2022 by the authors.
Recent Advancements in Developments of Novel Fluorescent Probes: In Cellulo Recognitions of Alkaline Phosphatases
(MDPI, 2022) Dasnur Nanjappa, M.; Pandith, A.; Sankaran, S.; Dorairaj, D.P.; Reddy, A.A.; Ramesh, H.P.B.
Alkaline phosphatase (ALP) is one of the vital phospho-ester bond cleaving biocatalysts that has inevitable significance in cellular systems, viz., early-stage osteoblast differentiation, cell integrity in tissues, bone mineralization, cancer biomarker, liver dysfunction, cellular osmotic pressure, protein folding and many more. Variation from optimal levels of ALP in intra and extracellular fluids can cause severe diseases, including death. Due to these reasons, ALP is considered as a vital biomarker for various preclinical and medical diagnosis. Fluorescence image-based diagnosis is the most widely used method, owing to its simplicity, robustness, non-invasive properties and excellent spatio-temporal resolution (up to the nM/pM level), as compared to conventional analytical techniques, such as the electroanalytical method, nuclear magnetic resonance (NMR) and high-performance liquid chromatography (HPLC). Most of the reviews reported for ALP’s recognition in the literature scarcely explain the structurally related, photophysical and biophysical parameters; and the sub-cellular localizations. Considering these facts, in order to enhance the opto-analytical parameters of fluorescence-based diagnostic materials at the cellular level, herein we have systematically documented recent developments in the opto-analytical capabilities of quencher-free probes for ALP, used in in vitro (biological buffers) to in cellulo conditions, along with in vivo models. © 2022 by the authors.